ArticleAmerican journal of hypertension2016
Hemodynamics and Vascular Hypertrophy in African Americans and Caucasians With High Blood Pressure.
Article in American journal of hypertension, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- The Autonomic Nervous System and Hypertension: Ethnic Differences and Psychosocial Factors.Current cardiology reports · 2019Review
- Hemodynamic profile and compensation deficit in African and European Americans during physical and mental stress.Biological psychology · 2019Article
- Disparities in Hypertension Among African-Americans: Implications of Insufficient Sleep.Current hypertension reports · 2018Review
- Circadian hemodynamics in men and women with high blood pressure: dipper vs. nondipper and racial differences.Journal of hypertension · 2018Article
- Impact of Racial Discrimination and Hostility on Adrenergic Receptor Responsiveness in African American Adults.Psychosomatic medicineArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundHypertension in African Americans is characterized by greater systemic vascular resistance (SVR) compared with Caucasian Americans, but the responsible mechanisms are not known. The present study sought to determine if peripheral vascular hypertrophy is a potential mechanism contributing to elevated SVR in African Americans with high blood pressure (BP).
methodsIn a biracial sample of 80 men and women between the ages of 25 and 45 years, with clinic BP in the range 130/85-160/99mm Hg, we assessed cardiac output and SVR, in addition to BP. Minimum forearm vascular resistance (MFVR), a marker of vascular hypertrophy, also was assessed.
resultsSVR was elevated in African Americans compared with Caucasians (P < 0.001). Regression models indicated that age, body mass index, 24-hour diastolic BP, and ethnicity were significant predictors of SVR. There was also a significant interaction between ethnicity and MFVR in explaining SVR in the study sample. In particular, there was a significant positive association between MFVR and SVR among African Americans (P = 0.002), whereas the association was inverse and not statistically significant among Caucasians (P = 0.601).
conclusionHypertrophy of the systemic microvasculature may contribute to the elevated SVR that is characteristic of the early stages of hypertension in African American compared with Caucasians.
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