Trial reportJournal of veterinary internal medicine2016
The Effect of Fasting Duration on Baseline Blood Glucose Concentration, Blood Insulin Concentration, Glucose/Insulin Ratio, Oral Sugar Test, and Insulin Response Test Results in Horses.
Trial report in Journal of veterinary internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Diagnostic evaluation of insulin and glucose dynamics in light-breed horses receiving dexamethasone.The Canadian veterinary journal = La revue veterinaire canadienne · 2022Article
- Comparison of insulin sensitivity between healthy neonatal foals and horses using minimal model analysis.PloS one · 2022Article
- Changes Associated with the Peri-Ovulatory Period, Age and Pregnancy in ACTH, Cortisol, Glucose and Insulin Concentrations in Mares.Animals : an open access journal from MDPI · 2021Article
- Chromium propionate increases insulin sensitivity in horses following oral and intravenous carbohydrate administration.Journal of animal science · 2020Article
- Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation.Journal of veterinary internal medicine · 2020Article
- Immunoreactive insulin stability in horses at risk of insulin dysregulation.Journal of veterinary internal medicine · 2019Article
- Effect of thyrotropin-releasing hormone stimulation testing on the oral sugar test in horses when performed as a combined protocol.Journal of veterinary internal medicine · 2019Article
- Evaluation of combined testing to simultaneously diagnose pituitary pars intermedia dysfunction and insulin dysregulation in horses.Journal of veterinary internal medicine · 2019Article
- Comparison of the glucose and insulin responses of horses to 2 formulations of corn syrup.The Canadian veterinary journal = La revue veterinaire canadienne · 2019Article
- ECEIM consensus statement on equine metabolic syndrome.Journal of veterinary internal medicine · 2019Article
- Repeatability of Oral Sugar Test Results, Glucagon-Like Peptide-1 Measurements, and Serum High-Molecular-Weight Adiponectin Concentrations in Horses.Journal of veterinary internal medicine · 2017Article
- Value of measuring markers of lipid metabolism in horses during an oral glucose test.Journal of veterinary internal medicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPublished descriptions of the oral sugar test (OST) and insulin response test (IRT) have been inconsistent when specifying the protocol for fasting horses before testing. The purpose of our study was to examine the effect of fasting duration on blood glucose concentration, blood insulin concentration, glucose/insulin ratio, OST, and IRT results in horses. ANIMALS: Ten healthy adult horses. PROCEDURES: Both OST and IRT were performed on horses without fasting and after fasting for 3, 6, and 12 hours. Thus, 8 tests were performed per horse in a randomized order. Blood collected at the initial time point of the OST was analysed for both blood glucose and serum insulin concentrations so that baseline concentrations and the glucose/insulin ratio could be determined. Unless fasted, horses had free-choice access to grass hay.
resultsThere was no effect of fasting and fasting duration on blood glucose concentration, serum insulin concentration, glucose/insulin ratio, or the OST. Response to insulin in the IRT was decreased in fasted horses. The effect increased with fasting duration, with the least response to insulin administration after a 12-hour fast. CONCLUSIONS AND CLINICAL RELEVANCE: These data indicate that insulin sensitivity is not a fixed trait in horses. Fasting a horse is not recommended for a glucose/insulin ratio or IRT, and fasting a horse for 3 hours is recommended for the OST.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.