Evidence map›Paper›PMID 27481215›Full record

ReviewGenetics, selection, evolution : GSE2016

Synergies between assisted reproduction technologies and functional genomics.

Pasqualino Loi, Paola Toschi, Federica Zacchini, Grazyna Ptak, Pier A Scapolo, Emanuele Capra, Alessandra Stella, Paolo Ajmone Marsan, John L Williams

Open access · goldAbstract readReview
In one paragraph

Review in Genetics, selection, evolution : GSE, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Pasqualino LoiLaboratory of Embryology, Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy. ploi@unite.it.
Paola ToschiLaboratory of Embryology, Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Federica ZacchiniLaboratory of Embryology, Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Grazyna PtakLaboratory of Embryology, Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Pier A ScapoloLaboratory of Embryology, Faculty of Veterinary Medicine, University of Teramo, Teramo, Italy.
Emanuele CapraInstitute of Agricultural Biology and Biotechnology, National Research Council, 26900, Lodi, Italy.
Alessandra StellaInstitute of Agricultural Biology and Biotechnology, National Research Council, 26900, Lodi, Italy.
Paolo Ajmone MarsanIstituto di Zootecnica, Università Cattolica del Sacro Cuore, Piacenza, Italy.
John L WilliamsDavies Research Centre, School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA, 5371, Australia.
University of Teramo · ITDeleted InstitutionPolish Academy of Sciences · PLUniversità Cattolica del Sacro Cuore · ITUniversity of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This review, is a synopsis of advanced reproductive technologies in farm animals, including the discussion of their limiting factors as revealed by the study of offspring derived from embryos produced in vitro and through cloning. These studies show that the problems of epigenetic mis-programming, which were reported in the initial stages of assisted reproduction, still persist. The importance of whole-genome analyses, including the methylome and transcriptome, in improving embryo biotechnologies in farm animals, are discussed. Genome editing approaches for the improvement of economically-relevant traits in farm animals are also described. Efficient farm animal embryo biotechnologies, including cloning and the most recent technologies such as genome editing, will effectively complement the latest strategies to accelerate genetic improvement of farm animals.

Indexed as

AnimalsAnimals, DomesticBiotechnologyBreedingCloning, OrganismEpigenesis, GeneticGene EditingGenomicsReproductive Techniques, Assisted

Identifiers

PMID27481215
PMCPMC4968447
OpenAlexW2505377518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.