Evidence map›Paper›PMID 27480977›Full record

SynthesisClinical rheumatology2016

The incidence of sexually acquired reactive arthritis: a systematic literature review.

Hayley J Denison, Elizabeth M Curtis, Michael A Clynes, Collette Bromhead, Elaine M Dennison, Rebecca Grainger

Open access · greenAbstract readSystematic Review
In one paragraph

Synthesis in Clinical rheumatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Recommendation on screening for chlamydia and gonorrhea in primary care for individuals not known to be at high risk.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Guideline
  2. [Reactive arthritis].Zeitschrift fur Rheumatologie · 2025
    Review
  3. Review
  4. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Review
  5. A practical approach to the diagnosis and management of chlamydia and gonorrhea.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Review
  6. A 2-pyridone amide inhibitor of transcriptional activity inAntimicrobial agents and chemotherapy · 2023
    Article
  7. Review
  8. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021
    Article
  9. Review
  10. Article
  11. Reactive Arthritis: Update.Current clinical microbiology reports · 2020
    Review
  12. Review
  13. Article
  14. Article
  15. Reactive arthritis: update 2018.Clinical rheumatology · 2018
    Review
  16. Article
  17. Barriers to sexually transmitted infection testing in New Zealand: a qualitative study.Australian and New Zealand journal of public health · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Hayley J DenisonSchool of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand. hayley.denison@vuw.ac.nz.
Elizabeth M CurtisMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.
Michael A ClynesMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom.
Collette BromheadCollege of Health, Massey University, Wellington, New Zealand.
Elaine M DennisonSchool of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand.
Rebecca GraingerRehabilitation Teaching and Research Unit, Department of Medicine, University of Otago Wellington, Wellington, New Zealand.
University of Southampton · GBMassey University · NZMRC Lifecourse Epidemiology Unit · GBUniversity of Otago · NZVictoria University of Wellington · NZ

Funding

Medical Research Council G0400491Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UU_12011/1Versus Arthritis 19583
6 · The paper itself

Abstract

Reactive arthritis (ReA) is an inflammatory spondyloarthritis occurring after infection at a distant site. Chlamydia trachomatis is proposed to be the most common cause of ReA, yet the incidence of sexually acquired ReA (SARA) has not been well established. We therefore carried out a systematic literature review to collate and critically evaluate the published evidence regarding the incidence of SARA. MEDLINE and EMBASE databases were searched using free-text and MeSH terms relating to infection and ReA. The title and abstract of articles returned were screened independently by two reviewers and potentially relevant articles assessed in full. Data was extracted from relevant articles and a risk of bias assessment carried out using a validated tool. Heterogeneity of study methodology and results precluded meta-analysis. The search yielded a total of 11,680 articles, and a further 17 were identified from review articles. After screening, 55 papers were assessed in full, from which 3 met the relevant inclusion criteria for the review. The studies reported an incidence of SARA of 3.0-8.1 % and were found to be of low to moderate quality. More studies are required to address the lack of data regarding the incidence of SARA. Specific and sensitive classification criteria must be developed in order for consistent classification and valid conclusions to be drawn. In clinical practice, it is recommended clinicians discuss the possibility of ReA developing at the time of STI diagnosis and to encourage patients to return if they experience any relevant symptoms.

Indexed as

Arthritis, ReactiveChlamydia InfectionsHumansIncidenceProhibitinsSexually Transmitted DiseasesProhibitinsIncidenceReactive arthritis < rheumatic diseasesSexually transmitted infectionsSystematic review

Identifiers

PMID27480977
PMCPMC5065716
OpenAlexW2502914496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.