Evidence map›Paper›PMID 27480285›Full record

ArticleEuropean biophysics journal : EBJ2016

Electrochemical impedance spectroscopy for black lipid membranes fused with channel protein supported on solid-state nanopore.

Muhammad S Khan, Noura S Dosoky, Bakhrom K Berdiev, John D Williams

Abstract read
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In one paragraph

Article in European biophysics journal : EBJ, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Galectin-3 Binding to αThe journal of physical chemistry. B · 2022
    Article
  4. Article
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  6. Article
  7. Review
  8. Article
  9. Article
  10. Cholesterol Increases Lipid Binding Rate and Changes Binding Behavior ofInternational journal of molecular sciences · 2018
    Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Muhammad S KhanElectrical and Computer Engineering Department, University of Alabama in Huntsville, Huntsville, AL, 35899, USA. mskhan7@illinois.edu.
Noura S DosokyBiotechnology Science and Engineering Program, University of Alabama in Huntsville, Huntsville, AL, 35899, USA.
Bakhrom K BerdievDepartment of Biomedical Sciences, Nazarbayev University School of Medicine, Astana, 010000, Kazakhstan.
John D WilliamsElectrical and Computer Engineering Department, University of Alabama in Huntsville, Huntsville, AL, 35899, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Black lipid membranes (BLMs) have been used for detecting single-channel activities of pore-forming peptides and ion channels. However, the short lifetimes and poor mechanical stability of suspended bilayers limit their applications in high throughput electrophysiological experiments. In this work, we present a synthetic solid-state nanopore functionalized with BLM fused with channel protein. A nanopore with diameter of ~180 nm was electrochemically fabricated in a thin silicon membrane. Folding and painting techniques were demonstrated for production of stable suspended BLMs followed by incorporation of transmembrane protein, ENaC. Membrane formation was confirmed by employing electrochemical impedance spectroscopy (EIS) in the frequency regime of 10

Indexed as

NanoporesBiosensing TechniquesCell MembraneDielectric SpectroscopyEpithelial Sodium ChannelsEpithelial Sodium ChannelsBlack lipid membranesElectrochemical impedance spectroscopyENaCNanobiosensorSiliconSolid-state nanoporeTransmembrane protein

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.