Evidence map›Paper›PMID 27479682›Full record

ArticleBiometrics2017

A framework for Bayesian nonparametric inference for causal effects of mediation.

Chanmin Kim, Michael J Daniels, Bess H Marcus, Jason A Roy

Abstract read
In one paragraph

Article in Biometrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Causal mediation and sensitivity analysis for mixed-scale data.Statistical methods in medical research · 2023
    Article
  5. Article
  6. Article
  7. Bayesian semi-parametric G-computation for causal inference in a cohort study with MNAR dropout and death.Journal of the Royal Statistical Society. Series C, Applied statistics · 2021
    Article
  8. Article
  9. Article
  10. A Semiparametric Bayesian Approach to Dropout in Longitudinal Studies with Auxiliary Covariates.Journal of computational and graphical statistics : a joint publication of American Statistical Association, Institute of Mathematical Statistics, Interface Foundation of North America · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Discussion of PENCOMP.Journal of the American Statistical Association · 2019
    Article
  15. Article
  16. Bayesian Approaches for Missing Not at Random Outcome Data: The Role of Identifying Restrictions.Statistical science : a review journal of the Institute of Mathematical Statistics · 2018
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Chanmin KimDepartment of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts 02115, U.S.A.
Michael J DanielsDepartment of Statistics and Data Sciences and Department of Integrative Biology, University of Texas at Austin, Austin, Texas 78712, U.S.A.
Bess H MarcusDepartment of Family Medicine and Public Health, University of California, San Diego, California 92093, U.S.A.
Jason A RoyDepartment of Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, U.S.A.

Funding

EXERCISE INSTRUCTION VIA PHONE OR PRINTR01HL064342 · NHLBI · MIRIAM HOSPITAL · PI MARCUS, BESS HYA · 2000 to 2009
$3.6M
BAYESIAN APPROACHES FOR MISSINGNESS AND CAUSALITY IN CANCER AND BEHAVIOR STUDIESR01CA183854 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI DANIELS, MICHAEL J · 2014 to 2019
$1.7M
Non-Parametric Bayesian Methods for Causal InferenceR01GM112327 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI ROY, JASON A · 2014 to 2017
$1.4M
COVARIANCE ESTIMATION FOR LONGITUDINAL CANCER DATAR01CA085295 · NCI · UNIVERSITY OF TEXAS AT AUSTIN · PI DANIELS, MICHAEL J · 2001 to 2012
$1.1M
NCI NIH HHS R01 CA085295NCI NIH HHS R01 CA183854NHLBI NIH HHS R01 HL064342NIGMS NIH HHS R01 GM112327
6 · The paper itself

Abstract

We propose a Bayesian non-parametric (BNP) framework for estimating causal effects of mediation, the natural direct, and indirect, effects. The strategy is to do this in two parts. Part 1 is a flexible model (using BNP) for the observed data distribution. Part 2 is a set of uncheckable assumptions with sensitivity parameters that in conjunction with Part 1 allows identification and estimation of the causal parameters and allows for uncertainty about these assumptions via priors on the sensitivity parameters. For Part 1, we specify a Dirichlet process mixture of multivariate normals as a prior on the joint distribution of the outcome, mediator, and covariates. This approach allows us to obtain a (simple) closed form of each marginal distribution. For Part 2, we consider two sets of assumptions: (a) the standard sequential ignorability (Imai et al., 2010) and (b) weakened set of the conditional independence type assumptions introduced in Daniels et al. (2012) and propose sensitivity analyses for both. We use this approach to assess mediation in a physical activity promotion trial.

Indexed as

Bayes TheoremHumansModels, StatisticalCausal inferenceDirichlet process mixtureSensitivity Analysis

Identifiers

PMID27479682
PMCPMC5288310

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.