ReviewCurrent opinion in pharmacology2016
Co-morbidity of PTSD and immune system dysfunction: opportunities for treatment.
Review in Current opinion in pharmacology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Lifetime posttraumatic stress disorder as a predictor of mortality: a systematic review and meta-analysis.BMC psychiatry · 2023Pooled it
- Immune response to vaccination in adults with mental disorders: A systematic review.Journal of affective disorders · 2022Pooled it
- Altered gene expression and PTSD symptom dimensions in World Trade Center responders.Molecular psychiatry · 2022Pooled it
- Pathophysiology-guided biomarkers and therapeutics for precision trauma medicine in polytrauma with musculoskeletal injuries.Military Medical Research · 2026Review
- Integrating multi-omics to reveal the causal effect of gut microbiota on post-traumatic stress disorder and potential drug target analysis.European journal of psychotraumatology · 2025Review
- Radiation effects research foundation-a view to the future.Carcinogenesis · 2025Article
- Psychological, neuroendocrine and inflammatory stress responses in women after miscarriage or stillbirth: investigating early psychobiological adaptations to potential traumatic events.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Telomere Dynamics in Post-Traumatic Stress Disorder: A Critical Synthesis.Biomedicines · 2025Review
- Physiology mechanisms of exercise for PTSD: a narrative review.Frontiers in psychology · 2025Review
- Clinical conceptualisation of PTSD in psilocybin treatment: disrupting a pre-determined and over-determined maladaptive interpretive framework.Therapeutic advances in psychopharmacology · 2025Review
- Effects of genetically predicted posttraumatic stress disorder on autoimmune phenotypes.Translational psychiatry · 2024Article
- Psychological interventions for cancer-related post-traumatic stress disorder: narrative review.BJPsych bulletin · 2024Review
- Association of homelessness and diet on the gut microbiome: a United States-Veteran Microbiome Project (US-VMP) study.mSystems · 2024Article
- Inescapable foot shock induces a PTSD-like phenotype and negatively impacts adult murine bone.Disease models & mechanisms · 2024Article
- Association between microbiome and the development of adverse posttraumatic neuropsychiatric sequelae after traumatic stress exposure.Translational psychiatry · 2023Article
- Peripheral inflammation over the course of a cognitive behavioral intervention in PTSD.Brain, behavior, & immunity - health · 2023Article
- The link between post-traumatic stress disorder and systemic lupus erythematosus.Brain, behavior, and immunity · 2023Review
- MDMA administration attenuates hippocampal IL-β immunoreactivity and subsequent stress-enhanced fear learning: An animal model of PTSD.Brain, behavior, & immunity - health · 2022Article
- Immunogenetics of posttraumatic stress disorder (PTSD) in women veterans.Brain, behavior, & immunity - health · 2022Article
- Neural correlates linking trauma and physical symptoms.Psychiatry research. Neuroimaging · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Posttraumatic stress disorder (PTSD) is defined as a psychiatric disorder; however, PTSD co-occurs with multiple somatic manifestations. People living with PTSD commonly manifest dysregulations in the systems that regulate the stress response, including the hypothalamic-pituitary-adrenal (HPA) axis, and development of a pro-inflammatory state. Additionally, somatic autoimmune and inflammatory diseases and disorders have a high rate of co-morbidity with PTSD. Recognition and understanding of the compounding effect that these disease states can have on each other, evidenced from poorer treatment outcomes and accelerated disease progression in patients suffering from co-morbid PTSD and/or other autoimmune and inflammatory diseases, has the potential to lead to additional treatment opportunities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.