Evidence map›Paper›PMID 27479176›Full record

ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2016

Epidemiology and etiology of influenza-like-illness in households in Vietnam; it's not all about the kids!

Diep Ngoc Thi Nguyen, Le Quynh Mai, Juliet E Bryant, Nguyen Le Khanh Hang, Le Nguyen Minh Hoa, Behzad Nadjm, Pham Quang Thai, Tran Nhu Duong, Dang Duc Anh, Peter Horby and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 38 citations in OpenAlex.

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  10. Molecular epidemiology of influenza, RSV, and other respiratory infections among children in Qatar: A six years report (2012-2017).International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020
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  17. Effects of temperature on hospitalisation among pre-school children in Hanoi, Vietnam.Environmental science and pollution research international · 2019
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Diep Ngoc Thi NguyenOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam.
Le Quynh MaiNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Juliet E BryantOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Nguyen Le Khanh HangNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Le Nguyen Minh HoaOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam.
Behzad NadjmOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Pham Quang ThaiNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Tran Nhu DuongNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Dang Duc AnhNational Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Peter HorbyOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
H Rogier van DoornOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam; Center for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Heiman F L WertheimOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam; Department of Medical Microbiology, Radboudumc, Nijmegen, Netherlands.
Annette FoxOxford University Clinical Research Unit and Wellcome Trust Major Overseas Programme, Vietnam; The University of Melbourne, Peter Doherty Institute for Infection and Immunity, Department of Microbiology and Immunology, Parkville, Victoria, Australia. Electronic address: annette.fox@unimelb.edu.au.
National Institute Of Hygiene And Epidemiology · VNUniversity of Oxford · GBOxford University Clinical Research Unit · VNRadboud University Nijmegen · NLThe University of Melbourne · AU

Funding

Wellcome Trust 077078/Z/05/ZWellcome Trust 081613/Z/06/Z
6 · The paper itself

Abstract

backgroundHousehold studies provide opportunities to understand influenza-like-illness (ILI) transmission, but data from (sub)tropical developing countries are scarce.

objectiveTo determine the viral etiology and epidemiology of ILI in households. STUDY

designILI was detected by active case finding amongst a cohort of 263 northern Vietnam households between 2008 and 2013. Health workers collected nose and throat swabs for virus detection by multiplex real-time RT-PCR.

resultsILI was detected at least once in 219 (23.7%) of 945 household members. 271 (62.3%) of 435 nose/throat swabs were positive for at least one of the 15 viruses tested. Six viruses predominated amongst positive swabs: Rhinovirus (28%), Influenza virus (17%), Coronavirus (8%), Enterovirus (5%), Respiratory syncytial virus (3%), Metapneumovirus virus (2.5%) and Parainfluenza virus 3 (1.8%). There was no clear seasonality, but 78% of episodes occurred in Winter/Spring for Influenza compared to 32% for Rhinovirus. Participants, on average, suffered 0.49 ILI, and 0.29 virus-positive ILI episodes, with no significant effects of gender, age, or household size. In contrast to US and Australian community studies, the frequency of ILI decreased as the number of household members aged below 5 years increased (p=0.006).

conclusionThe findings indicate the need for tailored ILI control strategies, and for better understanding of how local childcare practices and seasonality may influence transmission and the role of children.

Indexed as

Family CharacteristicsFamily HealthAdolescentAdultAgedAged, 80 and overChildChild, PreschoolFemaleHumansInfantInfant, NewbornMaleMiddle AgedMultiplex Polymerase Chain ReactionNasal CavityActive case findingCohortHousehold transmissionInfluenza-like-illnessRespiratory virusesVietnam

Identifiers

PMID27479176
PMCPMC4994428
OpenAlexW2498015092

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.