ArticleAnnals of surgical treatment and research2016
Effect of surgical timing and outcomes for appendicitis severity.
Article in Annals of surgical treatment and research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- The impact of timing on outcomes in appendicectomy: a systematic review and network meta-analysis.World journal of emergency surgery : WJES · 2024Pooled it
- The diagnostic significance of Doppler ultrasound assessment of superior mesenteric artery hemodynamic changes in acute suppurative appendicitis: an integrated analysis of systemic inflammation and oxidative stress.Frontiers in medicine · 2026Article
- Anticipating Urgency: Predictive Factors for Early Intervention in Appendicular Perforation.Cureus · 2024Article
- Effect of in-hospital delay on acute appendicitis severity: does time really matter?Updates in surgery · 2024Article
- Can Physicians Delay Appendectomy for One Night in Children With Acute Appendicitis?Middle East journal of digestive diseases · 2024Article
- Timing of surgical operation for patients with intra-abdominal infection: A systematic review and meta-analysis.World journal of gastrointestinal surgery · 2023Article
- Acute Appendicitis with Appendicolith and its Complication and Management: A Case Report.Cureus · 2023Article
- Management of appendicitis: appendicectomy, antibiotic therapy, or both?Annals of medicine and surgery (2012) · 2023Article
- Clinical course in children with equivocal appendicitis on computed tomography: a retrospective cohort study.Annals of surgical treatment and research · 2023Article
- Article
- Demonstration of a new entity of non-perforated appendicitis through studying cluster of appendicitis.Scientific reports · 2022Article
- Article
- Predictors of complicated appendicitis among patients presented to public referral hospitals in Harari region, Eastern Ethiopia: a case-control study.Surgery in practice and science · 2022Article
- Heart Rate Variability May Predict the Severity of Appendicitis: A Cross-Sectional Study.Bulletin of emergency and trauma · 2022Article
- Impact of COVID-19 on the care of acute appendicitis: a single-center experience in Korea.Annals of surgical treatment and research · 2021Article
- Acute appendicitis in the COVID-19 era: A complicated situation?Annals of medicine and surgery (2012) · 2021Article
- Nighttime Appendectomy is Safe and has Similar Outcomes as Daytime Appendectomy: A Study of 1198 Appendectomies.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021Article
- Inflammatory Markers and Duration of Symptoms Have a Close Connection With Diagnosis and Staging of Acute Appendicitis in Children.Frontiers in pediatrics · 2021Article
- Nationwide study of appendicitis in children.The British journal of surgery · 2019Article
- CT Scan Findings Can Predict the Safety of Delayed Appendectomy for Acute Appendicitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study was aimed to evaluate the effect of time of surgery for acute appendicitis on surgical outcomes to optimize the timing of appendectomies.
methodsMedical records of patients who underwent an appendectomy were reviewed to obtain data on time of symptom onset, time of hospital presentation, and start times of surgery. Surgical findings were used to define appendicitis as either uncomplicated or complicated. The uncomplicated group included patients with simple, focal, or suppurative appendicitis, and the complicated group included patients with gangrenous, perforated appendicitis or periappendiceal abscess formation. The 2 groups were analyzed by age, sex, and time.
resultsA total of 192 patients were analyzed. The mean time from symptom onset to start of operation showed a significant difference between both groups (1,652.9 minutes vs. 3,383.8 minutes, P < 0.001). The mean time from hospital visit to start of operation showed no difference between both groups (398.7 minutes vs. 402.0 minutes, P = 0.895). Operating within 24 hours of symptom onset had a relative risk of 1.738 (95% confidence interval, 1.319-2.425) for complications. Operating more than 36 hours after symptom onset was associated with an increased risk of postoperative ileus and a longer hospital stay.
conclusionComplicated appendicitis is associated with a delay in surgery from symptom onset rather than a delay at hospital arrival. Surgeons should take into account the time from symptom onset when deciding on the timing of appendectomy. We recommend that appendectomy be performed within 36 hours from symptom onset.
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