ArticleIranian Red Crescent medical journal2016
Efficacy of Traditional Medicine Product Henna and Hydrocortisone on Diaper Dermatitis in Infants.
Article in Iranian Red Crescent medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05427760 (Effect of Using Oxygen on the Diaper Dermatitis in Infants), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Using Oxygen on the Diaper Dermatitis in Infants
Who cites it
5 citing papers in PubMed, 20 citations in OpenAlex.
- Effects of argan spinosa oil in the treatment of diaper dermatitis in infants and toddlers: A quasi-experimental study.Journal of Taibah University Medical Sciences · 2023Article
- Efficacy of a Topical Formulation of Henna (Lawsonia Inermis Linnaeus) on the Itch and Wound Healing in Patients With Epidermolysis Bullosa: a Pilot Single-arm Clinical Trial.Dermatology practical & conceptual · 2022Article
- A new therapeutic horizon in diaper dermatitis: Novel agents with novel action.International journal of women's dermatology · 2021Review
- The Effect of Henna (International journal of preventive medicine · 2019Article
- The Effectiveness of a Topical Turmeric-Based Formulation on Contact Dermatitis: A Randomized, Double-Blind, Controlled Trial.Iranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDiaper dermatitis (DD) is a common inflammatory disorder in infants, including newborns.
objectivesThis study aimed to compare the effects of a traditional medicine product (containing natural henna oil 25%) and hydrocortisone 1% cream on DD in infants. PATIENTS AND
methodsIn a triple-blind, randomized trial, 82 children aged two years or less were randomly divided into two groups of 41 children each to receive either hydrocortisone ointment or henna medicinal product. Infants were treated 3 times a day for 5 days. The severity of dermatitis was assessed on the first, third, and fifth days using a six-point scale. The study was conducted in 2013 in a children teaching hospital in Qazvin, Iran.
resultsBoth groups showed an improvement in the severity of DD (mean DD severity on the first, third and fifth days, respectively, was 3.20, 1.39, and 1.20 in the henna group versus 3.20, 2.05, and 1.90 in the hydrocortisone group; P < 0.001). The henna group showed a better response when compared with the hydrocortisone group: the rate of improvement on the fifth day of treatment was 90.2% (37 of 41 children without erythema) in the former versus 61% (25 of 41 patients) in the latter (P = 0.042). No significant side effects were observed in both the groups.
conclusionsHenna, a traditional medicine product, can be considered an effective and appropriate treatment for DD in infants and children.
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Registered trials
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