Evidence map›Paper›PMID 27478561›Full record

ArticleEuropean journal of translational myology2016

Serum Response Factor in Muscle Tissues: From Development to Ageing.

Dario Coletti, Nissrine Daou, Medhi Hassani, Zhenlin Li, Ara Parlakian

Open access · goldAbstract read
In one paragraph

Article in European journal of translational myology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 54 citations in OpenAlex.

  1. ESR1 as a candidate gene for adolescent idiopathic scoliosis pathogenesis in North-West Indian population.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  12. Refining theAnimals : an open access journal from MDPI · 2022
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  19. Displaced Myonuclei in Cancer Cachexia Suggest Altered Innervation.International journal of molecular sciences · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Dario ColettiSorbonne University, UPMC, Department of Biological Adaptation and Ageing, IBPS, UMR 8256 CNRS, INSERM U1164, Paris, France; Dept of Anatomy, Histology, Forensic Medicine & Ortopedics, School of Medicine Sapienza University of Rome, Italy.
Nissrine DaouSorbonne University, UPMC , Department of Biological Adaptation and Ageing, IBPS, UMR 8256 CNRS, INSERM U1164, Paris, France.
Medhi HassaniSorbonne University, UPMC , Department of Biological Adaptation and Ageing, IBPS, UMR 8256 CNRS, INSERM U1164, Paris, France.
Zhenlin LiSorbonne University, UPMC , Department of Biological Adaptation and Ageing, IBPS, UMR 8256 CNRS, INSERM U1164, Paris, France.
Ara ParlakianSorbonne University, UPMC , Department of Biological Adaptation and Ageing, IBPS, UMR 8256 CNRS, INSERM U1164, Paris, France.
Centre National de la Recherche Scientifique · FRInserm · FRSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skeletal, cardiac and smooth muscle cells share various common characteristic features. During development the embryonic mesodermal layer contribute at different proportions to the formation of these tissues. At the functional level, contractility as well as its decline during ageing, are also common features. Cytoskeletal components of these tissues are characterized by various actin isoforms that govern through their status (polymerised versus monomeric) and their interaction with the myosins the contractile properties of these muscles. Finally, at the molecular level, a set of different transcription factors with the notable exception of Serum Response Factor SRF- which is commonly enriched in the 3 types of muscle- drive and maintain the differentiation of these cells (Myf5, MyoD, Myogenin for skeletal muscle; Nkx2.5, GATA4 for cardiomyocytes). In this review, we will focus on the transcription factor SRF and its role in the homeostasis of cardiac, smooth and skeletal muscle tissues as well as its behaviour during the age related remodelling process of these tissues with a specific emphasis on animal models and human data when available.

Indexed as

AgeingCre/loxPMuscle remodellingMuscle tissueSRF

Identifiers

PMID27478561
PMCPMC4942704
OpenAlexW2465504954

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.