ArticleNutrition research and practice2016
Leptin and uric acid as predictors of metabolic syndrome in jordanian adults.
Article in Nutrition research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Can biomarkers be used to improve diagnosis and prediction of metabolic syndrome in childhood cancer survivors? A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021Pooled it
- Application and Analysis of Random Forest and Support Vector Classification in Risk Prediction of Childhood Obesity and Hyperuricemia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Association between novel adiposity parameters and hyperuricemia: a cross-sectional study.Frontiers in nutrition · 2025Article
- The agreement of low lean mass with obesity using different definitions and its correlation with hyperuricemia.Frontiers in nutrition · 2024Article
- Association between the Weight-Adjusted Waist Index and Serum Uric Acid: A Cross-Sectional Study.International journal of clinical practice · 2023Article
- The prevalence of hyperuricemia and its correlates in Zhuang nationality, Nanning, Guangxi Province.Journal of clinical laboratory analysis · 2022Article
- Assessing the Causal Effects of Adipokines on Uric Acid and Gout: A Two-Sample Mendelian Randomization Study.Nutrients · 2022Article
- The Association Between Total Percent Fat and Serum Uric Acid in Adults.Frontiers in nutrition · 2022Article
- Leptin and the GA genotype of rs2167270 of theBiomedical reports · 2021Article
- Article
- Macronutrient intake and physical activity levels in individuals with and without metabolic syndrome: An observational study in an urban population.ARYA atherosclerosis · 2019Article
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Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesMetabolic syndrome (MetS) is a set of interrelated metabolic risk factors that increase the risk of cardiovascular morbidity and mortality. Studies regarding the specificity and sensitivity of serum levels of leptin and uric acid as predictors of MetS are limited. The aim of this study was to evaluate the serum levels of leptin and uric acid in terms of their specificity and sensitivity as predictors of MetS in the studied Jordanian group. SUBJECTS/
methodsIn this cross sectional study, 630 adult subjects (308 men and 322 women) were recruited from the King Hussein Medical Center (Amman, Jordan). The diagnosis of MetS was made according to the 2005 International Diabetes Federation criteria. Receiver operating characteristic curves were used to determine the efficacy of serum levels of leptin and uric acid as predictors of MetS in the studied Jordanian group.
resultsStudy results showed that for identification of subjects with MetS risk, area under the curve (AUC) for leptin was 0.721 and 0.683 in men and women, respectively. Serum uric acid levels in men showed no significant association with any MetS risk factors and no significant AUC, while uric acid AUC was 0.706 in women.
conclusionSerum leptin levels can be useful biomarkers for evaluation of the risk of MetS independent of baseline obesity in both men and women. On the other hand, serum uric acid levels predicted the risk of MetS only in women.
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