ArticleBiomicrofluidics2016
Microfluidic converging/diverging channels optimised for homogeneous extensional deformation.
Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Sheath-enhanced concentration and on-chip detection of bacteria from an extremely low-concentration level.Lab on a chip · 2025Article
- Recent Advances of PDMS In Vitro Biomodels for Flow Visualizations and Measurements: From Macro to Nanoscale Applications.Micromachines · 2024Review
- Blood Particulate Analogue Fluids: A Review.Materials (Basel, Switzerland) · 2021Review
- Interfacial Tension Measurements in Microfluidic Quasi-Static Extensional Flows.Micromachines · 2021Article
- Pathologic Shear and Elongation Rates Do Not Cause Cleavage of Von Willebrand Factor by ADAMTS13 in a Purified System.Cellular and molecular bioengineering · 2020Article
- A Microfluidic Deformability Assessment of Pathological Red Blood Cells Flowing in a Hyperbolic Converging Microchannel.Micromachines · 2019Article
- Optimization of flow-focusing devices for homogeneous extensional flow.Biomicrofluidics · 2018Article
- Preface to Special Topic: Invited Articles on Microfluidic Rheology.Biomicrofluidics · 2016Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
In this work, we optimise microfluidic converging/diverging geometries in order to produce constant strain-rates along the centreline of the flow, for performing studies under homogeneous extension. The design is examined for both two-dimensional and three-dimensional flows where the effects of aspect ratio and dimensionless contraction length are investigated. Initially, pressure driven flows of Newtonian fluids under creeping flow conditions are considered, which is a reasonable approximation in microfluidics, and the limits of the applicability of the design in terms of Reynolds numbers are investigated. The optimised geometry is then used for studying the flow of viscoelastic fluids and the practical limitations in terms of Weissenberg number are reported. Furthermore, the optimisation strategy is also applied for electro-osmotic driven flows, where the development of a plug-like velocity profile allows for a wider region of homogeneous extensional deformation in the flow field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.