ArticleThe open microbiology journal2016
Comparison Between Pathogen Associated Laboratory and Clinical Parameters in Early-Onset Sepsis of the Newborn.
Article in The open microbiology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Hemodynamic Assessment in Newborn Infants With Sepsis: A Prospective Observational Study.Cureus · 2026Article
- Prevalence and overlap of white blood cell counts, procalcitonin and C-reactive protein in neonates with invasive bacterial infections.Translational pediatrics · 2025Article
- Optimal use of β-lactams in neonates: machine learning-based clinical decision support system.EBioMedicine · 2024Article
- An Analysis of Predictive Factors for Severe Neonatal Infection and the Construction of a Prediction Model.Infection and drug resistance · 2023Article
- Neonatal sepsis-causing bacterial pathogens and outcome of trends of their antimicrobial susceptibility a 20-year period at a neonatal intensive care unit.Clinical and experimental pediatrics · 2022Article
- [Cut-off value of white blood cell count in the diagnosis of early-onset sepsis in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- [Accurate use of antibiotics for preterm infants with early-onset sepsis should be taken seriously].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2020Article
- Anti-microbial stewardship: antibiotic use in well-appearing term neonates born to mothers with chorioamnionitis.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo identify laboratory and clinical characteristics of different pathogens associated with early-onset sepsis (EOS) of the newborn.
methodsNewborns with EOS were retrospectively analyzed regarding laboratory and clinical parameters associated with the identified pathogen.
resultsWe identified 125 newborns having diagnosis of culture proven EOS between 1993 and 2011. One hundred cases had diagnosis of group B streptococci (GBS) infection (80%), 11 had Escherichia coli (8.8%), eight enterococci (6.4%), and six other pathogens (4.8%). White blood cell count (WBC), immature to total neutrophil (IT) ratio, and C-reactive protein (CRP) values did not differ between groups within the first 72 hours of life. Presence of high (>30000/µL) and low (<9000/µl) WBC was significantly less found compared with IT-ratio >0.2 in GBS and E.coli EOS. High WBC were more common found than low WBC in all groups. Gram positive pathogens were more common found in late preterm and term infants (84%), and gram negative pathogens more common in very low birth weight infants (64%). E. coli was significantly associated with lower gestational age and birth weight, respectively.
conclusionAn abnormal IT-ratio was a more common finding than an abnormal WBC in GBS and E. coli EOS. E. coli was significantly associated with prematurity.
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