Evidence map›Paper›PMID 27478488›Full record

ArticleTottel's journal of professional negligence2016

A Duty To Warn Relatives in Clinical Genetics: Arguably 'Fair just and reasonable' in English Law?

C Mitchell, M C Ploem, R C M Hennekam, J Kaye

Abstract read
In one paragraph

Article in Tottel's journal of professional negligence, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

C MitchellResearcher in Law, Centre for Health, Law and Emerging Technologies (HeLEX), Nuffield Department of Population Health, University of Oxford, Ewert House, Ewert Place, Oxford OX2 7DD.
M C PloemAcademic Legal Researcher, Department of Public Health, Academic Medical Centre, University of Amsterdam, PO Box 22660, Amsterdam, Netherlands.
R C M HennekamProfessor of Paediatrics and Translational Genetics, Department of Paediatrics, Academic Medical Centre, University of Amsterdam, PO Box 22660, Amsterdam, Netherlands.
J KayeProfessor of Health Law and Policy, Centre for Health, Law and Emerging Technologies (HeLEX), Nuffield Department of Population Health, University of Oxford, Ewert House, Ewert Place, Oxford OX2 7DD. JK is funded under Wellcome Trust Award 096599/2/11/Z. The views expressed in this publication are those of the authors and not those of any supporting institutions.

Funding

Wellcome Trust 096599
6 · The paper itself

Abstract

The use of 'next-generation' genetic sequencing technology that allows the sequencing of large parts, or even the entirety, of a patient's genome is advancing rapidly in the UK and around the world. This is set to greatly increase the level of health information that will be of relevance to relatives and the latest medical guidance advises that there is a professional duty to consider warning a patient's relatives of a serious genetic risk in limited circumstances. However, the High Court in

Identifiers

PMID27478488
PMCPMC4962911

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.