ArticleSarcoma2016
Immediate versus Delayed Sarcoma Reconstruction: Impact on Outcomes.
Article in Sarcoma, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Comparison of Outcomes between Prolonged Neoadjuvant Chemotherapy followed by Delayed Surgery and Immediate Surgery with Adjuvant Chemotherapy in Osteosarcoma Patients: A Systematic Review and Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2025Pooled it
- A Systematic Review and Meta-Analysis of Negative Wound Pressure Therapy Use in Soft Tissue Sarcoma Resection.The Iowa orthopaedic journal · 2023Pooled it
- [Primary and secondary microsurgical reconstruction in soft tissue sarcomas].Chirurgie (Heidelberg, Germany) · 2026Review
- [Clinical efficacy of thinned free flaps in reconstructing the wounds following excision of malignant extremity tumors].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Article
- Review
- A Two-Step Approach to the Surgical Treatment of Soft-Tissue Sarcomas.Current oncology (Toronto, Ont.) · 2024Observational
- Single-Stage Free Flap Reconstruction Following Extremity Sarcoma Resection: a Regional Cancer Center Experience.Indian journal of surgical oncology · 2024Article
- Inflammatory prognostic scoring systems are risk factors for surgical site infection following wide local excision of soft tissue sarcoma.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- Microsurgical Reconstruction in Orthopedic Tumor Resections as Part of a Multidisciplinary Surgical Approach for Sarcomas of the Extremities.Life (Basel, Switzerland) · 2022Review
- One-Stage Soft Tissue Reconstruction Following Sarcoma Excision: A Personalized Multidisciplinary Approach Called "Orthoplasty".Journal of personalized medicine · 2020Article
- A comparison of delayed versus immediate reconstruction following lower-extremity sarcoma resection.Archives of plastic surgery · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Sarcoma is a rare malignancy, and more recent management algorithms emphasize a multidisciplinary approach and limb salvage, which has resulted in an increase in overall survival and limb preservation. However, limb salvage has resulted in a higher rate of wound complications. Objective. To compare the complications between immediate and delayed (>three weeks) reconstruction in the multidisciplinary limb salvage sarcoma patient population. Methods. A ten-year retrospective review of patients who underwent sarcoma resection was performed. The outcome of interest was wound complication in the postoperative period based on timing of reconstruction. We defined infection as any infection requiring intravenous antibiotics, partial flap failure as any flap requiring a debridement or revision, hematoma/seroma as any hematoma/seroma requiring drainage, and wound dehiscence as a wound that was not completely intact by three weeks postoperatively. Results. 70 (17 delayed, 53 immediate) patients who underwent sarcoma resection and reconstruction met the inclusion criteria. Delayed reconstruction significantly increased the incidence of postoperative wound infection and wound dehiscence. There was no difference in partial or total flap loss, hematoma, or seroma between the two groups. Discussion and Conclusion. Immediate reconstruction results in decreased wound complications may reduce the morbidity associated with multidisciplinary treatment in the limb salvage sarcoma patient.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.