ArticleJournal of Korean medical science2016
Cross-Reactivity between Oak and Birch Pollens in Korean Tree Pollinosis.
Article in Journal of Korean medical science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Profilin isoallergens, major but not immunodominant, from Korean melon.The World Allergy Organization journal · 2026Article
- Characterization of Pana g 1, an important cause of pollen-food allergy syndrome from Korean ginseng,The World Allergy Organization journal · 2026Article
- Update on hazelnut allergy: Allergen characterization, epidemiology, food processing technique and detecting strategy.Comprehensive reviews in food science and food safety · 2025Review
- Neglected but Clinically Relevant Allergens in Korea.Current allergy and asthma reports · 2024Review
- Quantification of Que ac 1 and Standardization of Pollen Extract from Sawtooth Oak, the Most Important Cause of Spring Pollinosis in Korea.Allergy, asthma & immunology research · 2021Article
- Sensitization profile to sawtooth oak component allergens and their clinical implications.Journal of clinical laboratory analysis · 2021Article
- Allergens of Regional Importance in Korea.Frontiers in allergy · 2021Review
- Stability of extracts from pollens of allergenic importance in Korea.The Korean journal of internal medicine · 2020Article
- Purification and Characterization of Pathogenesis Related Class 10 Panallergens.Foods (Basel, Switzerland) · 2019Article
- Clinical Features and Culprit Food Allergens of Korean Adult Food Allergy Patients: A Cross-Sectional Single-Institute Study.Allergy, asthma & immunology research · 2019Article
- Validation of PROTIA™ Allergy-Q 64 Atopy® as a Specific IgE Measurement Assay for 10 Major Allergen Components.Allergy, asthma & immunology research · 2019Article
- Subcutaneous Immunotherapy in Patients with Fagales Pollen-Induced Oral Allergy Syndrome.Yonsei medical journal · 2019Article
- Comparison between Newly Developed and Commercial Inhalant Skin Prick Test Reagents Using In Vivo and In Vitro Methods.Journal of Korean medical science · 2018Article
- Article
- Immunoglobulin E-Mediated Autoimmunity.Frontiers in immunology · 2018Review
- Comparison of the ImmunoCAP Assay and AdvanSure™ AlloScreen Advanced Multiplex Specific IgE Detection Assay.Yonsei medical journal · 2017Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oak and birch trees belong to Fagales order. Specific IgE to pollen allergens of both trees are frequently found in Korea pollinosis patients. Oak trees which comprise 40% of forest area are common in Korea. However, birch trees are sparse. We compared the allergenicity of pollen extracts of white oak, sawtooth and Mongolian oaks which are prevalent species in Korea, with the pollen extract of birch. The cross-reactivity of four pollen extracts was examined with pooled sera of 12 patients by ELISA, immunoblotting and CAP inhibitions. A protein of 17 kDa, putatively homologous to a major birch allergen Bet v 1, displayed strong IgE reactivity from white oak and sawtooth oak pollen extract but not from Mongolian oak pollen. Notably, a 23-kDa protein from sawtooth and white oaks showed strong IgE reactivity and inhibited by Bet v 1. IgE binding to white oak was inhibited a maximum of 94.6% by white oak, 93.4% by sawtooth oak, 83.2% by Mongolian oak, and 68.8% by birch. Furthermore, sawtooth oak, white oak, and Mongolian oak extracts were able to inhibit up to 78.5%, 76.6% and 67.3% of IgE binding to birch extract, while birch extract itself inhibited up to 94.3%. Specific IgE to Bet v 1 was inhibited a maximum of 79.1% by sawtooth oak, 77.4% by white oak, and 72.7% by Mongolian oak, while 81.5% inhibition was shown by birch. Bet v 1 was able to partially inhibit its homologous molecules from sawtooth oak and white oak in immunoblotting. Birch pollen extract was found to be cross-reactive primarily with Bet v 1-homologous allergen from oak pollens in Korea pollinosis patients. Considering the sparseness of birch tree in Korea, oak, especially sawtooth oak may be the main cause of tree pollinosis in Korea, rather than birch.
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