Evidence map›Paper›PMID 27478320›Full record

ArticleChinese journal of cancer research = Chung-kuo yen cheng yen chiu2016

Expanded endoscopic therapy criteria should be cautiously used in intramucosal gastric cancer.

Hongshan Wang, Heng Zhang, Cong Wang, Yong Fang, Xuefei Wang, Weidong Chen, Fenglin Liu, Kuntang Shen, Xinyu Qin, Zhenbin Shen and 1 more

Abstract read
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In one paragraph

Article in Chinese journal of cancer research = Chung-kuo yen cheng yen chiu, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. [Characteristics of lymph node metastasis and evaluating the efficacy of endoscopic submucosal dissection in early gastric cancer].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020
    Article
  3. Assessment of lymphatic flow based on the sentinel node concept in early gastric adenocarcinoma that satisfies expanded endoscopic resection criteria.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hongshan WangDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Heng ZhangDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Cong WangDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Yong FangDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Xuefei WangDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Weidong ChenDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Fenglin LiuDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Kuntang ShenDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Xinyu QinDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Zhenbin ShenDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.
Yihong SunDepartment of General Surgery, Zhongshan Hospital, General Surgery Research Institute, Fudan University, Shanghai 200032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAccurate estimation of lymph node metastasis (LNM) in intramucosal gastric cancer is essential to select less invasive treatment options and even avoid surgery. The aim of this study was to evaluate combined clinicopathological features to predict the presence of LNM.

methodsA retrospective review of data from 386 intramucosal gastric cancer patients who underwent gastrectomy with extended lymphadenectomy from 2003 to 2010 was conducted. The mutual relation between clinicopathological characteristics and LNM was analyzed.

resultsLNM was detected in 40 (10.4%) of the 386 patients. Histological type and vascular or lymphatic invasion presence showed a positive correlation with LNM occurrence by univariate analysis. Multivariate analysis revealed that histological type was the only factor associated with LNM. Combined clinicopathologic characteristics would be more predictable for LNM. We found no LNM when we used combined clinicopathological characteristics conforming to Japanese absolute indications for endoscopic therapy. The LNM rate was as high as 8.7% when Japanese expanded criteria were used. Univariate analysis in cancer conformity to expand endoscopic submucosal dissection (ESD) indication also revealed that the undifferential type was the only significant factor for LNM.

conclusionsIt was possible to predict intramucosal gastric cancer cases without LNM using combined clinicopathological characteristic analysis. Extended indication for ESD should be cautiously used for intramucosal gastric cancer patients.

Indexed as

early gastric cancerendoscopic therapyintramucosal cancerLymph node metastasis

Identifiers

PMID27478320
PMCPMC4949280

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.