Evidence map›Paper›PMID 27478291›Full record

ArticleJournal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986)2016

Quantification of the oxygen uptake rate in a dissolved oxygen controlled oscillating jet-driven microbioreactor.

Timothy V Kirk, Marco Pc Marques, Anand N Pallipurath Radhakrishnan, Nicolas Szita

Open access · hybridAbstract read
In one paragraph

Article in Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Timothy V KirkDepartment of Biochemical Engineering University College London Bernard Katz Building, Gordon Street London WC1H 0AH UK.
Marco Pc MarquesDepartment of Biochemical Engineering University College London Bernard Katz Building, Gordon Street London WC1H 0AH UK.
Anand N Pallipurath RadhakrishnanDepartment of Biochemical Engineering University College London Bernard Katz Building, Gordon Street London WC1H 0AH UK.
Nicolas SzitaDepartment of Biochemical Engineering University College London Bernard Katz Building, Gordon Street London WC1H 0AH UK.
University College London · GB

Funding

Biotechnology and Biological Sciences Research Council BB/I00484X/1
6 · The paper itself

Abstract

backgroundMicrobioreactors have emerged as a new tool for early bioprocess development. The technology has advanced rapidly in the last decade and obtaining real-time quantitative data of process variables is nowadays state of the art. In addition, control over process variables has also been achieved. The aim of this study was to build a microbioreactor capable of controlling dissolved oxygen (DO) concentrations and to determine oxygen uptake rate in real time.

resultsAn oscillating jet driven, membrane-aerated microbioreactor was developed without comprising any moving parts. Mixing times of ∼7 s, and k

conclusionThe results highlight the potential of DO-controlled microbioreactors to obtain real-time information on oxygen uptake rate, and by extension on cellular metabolism for a variety of cell types over a broad range of processing conditions. © 2015 The Authors. Journal of Chemical Technology & Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

microbioreactormicrofluidicsmixingoxygen controloxygen uptake rateSaccharomyces cerevisiae

Identifiers

PMID27478291
PMCPMC4950047
OpenAlexW1927333145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.