Evidence map›Paper›PMID 27478217›Full record

ArticleJournal of food science and technology2016

In vitro antioxidant, anti-diabetic and antilipemic potentials of quercetagetin extracted from marigold (Tagetes erecta L.) inflorescence residues.

Weiyou Wang, Honggao Xu, Hua Chen, Kedong Tai, Fuguo Liu, Yanxiang Gao

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of food science and technology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 73 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Predicting antioxidant activity of compounds based on chemical structure using machine learning methods.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2024
    Article
  9. Article
  10. Article
  11. Antibacterial effects of quercetagetin are significantly enhanced upon conjugation with chitosan engineered copper oxide nanoparticles.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. UPLC-ESI-QTOF-MS Profiling of Phenolic Compounds fromMolecules (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Effect of Natural Antioxidants from Marigolds (Molecules (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weiyou WangBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food From Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Box 112, No.17 Qinghua East Road, Haidian District, Beijing, 100083 China.
Honggao XuBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food From Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Box 112, No.17 Qinghua East Road, Haidian District, Beijing, 100083 China.
Hua ChenBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food From Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Box 112, No.17 Qinghua East Road, Haidian District, Beijing, 100083 China.
Kedong TaiBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food From Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Box 112, No.17 Qinghua East Road, Haidian District, Beijing, 100083 China.
Fuguo LiuBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food From Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Box 112, No.17 Qinghua East Road, Haidian District, Beijing, 100083 China.
Yanxiang GaoBeijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food From Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Box 112, No.17 Qinghua East Road, Haidian District, Beijing, 100083 China.
China Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quercetagetin, the major flavonoid in marigold (Tagetes erecta L.) inflorescence residues was extracted and purified. The content of quercetagetin after the purification was 89.91 ± 0.26 %. The in vitro antioxidant activity of quercetagetin and its potential in controlling diabetes mellitus and obesity were investigated and compared to quercetin and rutin. The 50 % inhibitory concentration (IC50) values of quercetagetin on scavenging 1, 1-diphenyl-2-picrylhydrazyl (DPPH), 2,2-azinobis-(3-ethylbenzothiazolin-6-sulfonic acid) (ABTS) and hydroxyl radicals were 27.12 ± 1.31 μmol/L, 12.16 ± 0.56 μmol/L and 1833.97 ± 6.66 μmol/L, respectively. The IC50 values of quercetagetin on α-glucosidase, α-amylase and pancreatic lipase were 180.11 ± 3.68 μmol/L, 137.71 ± 3.55 μmol/L and 2327.58 ± 12.37 μmol/L, respectively. These results indicated that quercetagetin exhibited strong in vitro antioxidant, anti-diabetic and antilipemic activities. Lineweaver-Burk plots analysis elucidated that quercetagetin inhibited α-glucosidase and α-amylase non-competitively, while its inhibition against pancreatic lipase was involved in a mixed-type pattern. Moreover, strong correlations were found between ABTS(·+)/DPPH(·) scavenging activities and lipase inhibitory activity (R (2) > 0.90), as well as ·OH scavenging activity and α-amylase inhibitory activity (R (2) = 0.8967).

Indexed as

Diabetes mellitusEnzyme inhibitionMarigold (Tagetes erecta L.) inflorescence residuesPancreatic lipaseQuercetagetin

Identifiers

PMID27478217
PMCPMC4951414
OpenAlexW2470137395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.