Evidence map›Paper›PMID 27478133›Full record

Trial reportJournal of geriatric oncology2016

Physical resilience of older cancer survivors: An emerging concept.

Wei Duan-Porter, Harvey J Cohen, Wendy Demark-Wahnefried, Richard Sloane, Jane F Pendergast, Denise C Snyder, Miriam C Morey

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of geriatric oncology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Evaluating a shared care pathway intervention for people receiving chemotherapy to reduce post-treatment unplanned hospital presentations: a randomised controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Ageing and physical resilience after health stressors.Stress and health : journal of the International Society for the Investigation of Stress · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Measuring Biologic Resilience in Older Cancer Survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Review
  16. Quantifying and Classifying Physical Resilience Among Older Adults: The Health, Aging, and Body Composition Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  17. Article
  18. Resilience in Cancer Patients.Frontiers in psychiatry · 2019
    Review
  19. Article
  20. Response to Ukraintseva et al. Letter: Resilience Versus Robustness in Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wei Duan-PorterHealth Services Research and Development, Durham VA Medical Center, Durham, NC, USA; Department of Medicine, Duke University School of Medicine, Durham, NC, USA; Duke University Claude D. Pepper Older Americans Independence Center, Durham, NC, USA. Electronic address: wei.duan-porter@duke.edu.
Harvey J CohenDepartment of Medicine, Duke University School of Medicine, Durham, NC, USA; Duke University Claude D. Pepper Older Americans Independence Center, Durham, NC, USA; Duke University Center for the Study of Aging and Human Development, Durham, NC, USA; Geriatrics Research, Education and Clinical Center, Durham VA Medical Center, Durham, NC, USA.
Wendy Demark-WahnefriedDepartment of Preventive Medicine, Department of Nutrition Sciences, University of Alabama, Birmingham, AL, USA; Comprehensive Cancer Center, University of Alabama, Birmingham, AL, USA.
Richard SloaneDuke University Claude D. Pepper Older Americans Independence Center, Durham, NC, USA; Duke University Center for the Study of Aging and Human Development, Durham, NC, USA; Geriatrics Research, Education and Clinical Center, Durham VA Medical Center, Durham, NC, USA.
Jane F PendergastDuke University Claude D. Pepper Older Americans Independence Center, Durham, NC, USA; Duke University Center for the Study of Aging and Human Development, Durham, NC, USA; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC, USA.
Denise C SnyderDuke Office of Clinical Research, Duke University School of Medicine, Durham, NC, USA.
Miriam C MoreyDepartment of Medicine, Duke University School of Medicine, Durham, NC, USA; Duke University Claude D. Pepper Older Americans Independence Center, Durham, NC, USA; Duke University Center for the Study of Aging and Human Development, Durham, NC, USA; Geriatrics Research, Education and Clinical Center, Durham VA Medical Center, Durham, NC, USA.
Duke University · USDurham VA Medical Center · USUniversity of Alabama at Birmingham · US

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI Virginia B Kraus · 2006 to 2026
$24.6M
RENEW Research-out to ENhancE Wellness Older SurvivorsR01CA106919 · NCI · DUKE UNIVERSITY · PI DEMARK-WAHNEFRIED, WENDY · 2004 to 2007
$2.1M
NCI NIH HHS R01 CA106919NIA NIH HHS P30 AG028716
6 · The paper itself

Abstract

objectivesTo characterize factors contributing to physical resilience in older cancer survivors, as demonstrated by resistance to decline or recovery (resilience). MATERIALS AND

methodsWe conducted a secondary analysis of data from a randomized controlled trial of cancer survivors ≥65years old and ≥5years from cancer diagnoses. Physical function was assessed quarterly over 2years, with Short-Form 36 physical function subscale. Participants with ≥2 follow-up assessments (n=594) were evaluated for physical resilience: 1) Resistance was defined as lack of any decline, where decline was a drop of ≥13 points, and 2) resilience (i.e., recovery) was defined as regaining ≥50% of lost function, subsequent to decline.

resultsMean age was 73.1years and 89.1% were Caucasian. Forty-nine percent (n=289) were resistant to decline in function; these individuals were younger, had higher education and income, were more likely to be Caucasian, and had higher baseline physical function (mean difference [MD] 7.8 points, 95% CI 5.0-10.8) and general health (MD 7.5 points, 95% CI 4.9-10.1). Fifty-seven percent (n=137 of 239) demonstrated resilience, with 91.2% (n=125) recovering within 6months of declines; these participants had higher baseline physical function (MD 6.6 points, 95% CI 1.8-11.4), but similar pre-decline function. More participants who were resistant, and more who showed resilience, reported high self-efficacy and social support.

conclusionsThe majority of older cancer survivors exhibited physical resilience; this was associated with high baseline health, physical function, self-efficacy, and social support. Assessing and targeting psychosocial factors may be important for interventions seeking to promote physical resilience.

Indexed as

Resilience, PsychologicalActivities of Daily LivingAgedCancer SurvivorsExerciseFemaleHumansMaleRecovery of FunctionSelf EfficacySocial SupportSocioeconomic FactorsUnited StatesCancer survivorsFunctional declinePhysical resilienceRecoveryResistance

Identifiers

PMID27478133
PMCPMC5159214
OpenAlexW2490289821

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.