Evidence map›Paper›PMID 27478061›Full record

ArticleAutism research : official journal of the International Society for Autism Research2017

Serotonin neuron abnormalities in the BTBR mouse model of autism.

Yue-Ping Guo, Kathryn G Commons

Open access · greenAbstract read
In one paragraph

Article in Autism research : official journal of the International Society for Autism Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  10. Altered Serotonin 2A (5-HTFrontiers in pharmacology · 2022
    Article
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  18. p38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Yue-Ping GuoDepartment of Anesthesiology, Second Affiliated Hospital, Harbin Medical University, Harbin, China.
Kathryn G CommonsDepartment of Anesthesiology, Perioperative, and Pain Medicine, Boston Children's Hospital; Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts.
Harbin Medical University · CNHarvard University · US

Funding

VENTRAL MEDULLA, BREATHING, AND CENTRAL CHEMORECEPTIONP01HD036379 · NICHD · HARVARD MEDICAL SCHOOL · PI KINNEY, HANNAH CHASE · 1998 to 2017
$32.2M
Topography of Serotonin DysfunctionR01DA021801 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI COMMONS, KATHRYN G · 2007 to 2018
$3.6M
NICHD NIH HHS P01 HD036379NIDA NIH HHS R01 DA021801
6 · The paper itself

Abstract

The inbred mouse strain BTBR T

Indexed as

AnimalsAutistic DisorderChromatography, High Pressure LiquidDisease Models, AnimalMiceMice, Inbred C57BLMice, Inbred StrainsNeuronsSerotoninSerotonindorsal raphelhippocampusmedian raphemonoaminenorepinephrineSERTswim

Identifiers

PMID27478061
PMCPMC5518607
OpenAlexW2476581217

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.