ArticleNeuron2016
Distinct Subthreshold Mechanisms Underlying Rate-Coding Principles in Primate Auditory Cortex.
Article in Neuron, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Acoustic Flutter Processing in the Inferior Colliculus of Awake Marmosets: Complementary Rate Coding Modulated by Acoustic Parameters.Neuroscience bulletin · 2026Article
- Behavioral engagement facilitates auditory neuron responses beyond their receptive fields.PLoS biology · 2026Article
- Neural Response Reliability as a Marker of the Transition of Neural Codes along Auditory Pathways.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Temporal merging into pitch with click train in the macaque auditory cortex.National science review · 2025Article
- Location-specific neural facilitation in marmoset auditory cortex.Nature communications · 2025Article
- Representation of conspecific vocalizations in amygdala of awake marmosets.National science review · 2023Article
- Differential Recovery of Submodality Touch Neurons and Interareal Communication in Sensory Input-Deprived Area 3b and S2 Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Distinct neuronal types contribute to hybrid temporal encoding strategies in primate auditory cortex.PLoS biology · 2022Article
- Mesoscopic landscape of cortical functions revealed by through-skull wide-field optical imaging in marmoset monkeys.Nature communications · 2022Article
- Oscillatory Entrainment of the Frequency-following Response in Auditory Cortical and Subcortical Structures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Intracellular neuronal recording in awake nonhuman primates.Nature protocols · 2020Article
- Precision multidimensional neural population code recovered from single intracellular recordings.Scientific reports · 2020Article
- The role of adaptation in generating monotonic rate codes in auditory cortex.PLoS computational biology · 2020Article
- Spectral tuning of adaptation supports coding of sensory context in auditory cortex.PLoS computational biology · 2019Article
- Propagation of temporal and rate signals in cultured multilayer networks.Nature communications · 2019Article
- The rough sound of salience enhances aversion through neural synchronisation.Nature communications · 2019Article
- Single-Cell Membrane Potential Fluctuations Evince Network Scale-Freeness and Quasicriticality.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Subthreshold Activity Underlying the Diversity and Selectivity of the Primary Auditory Cortex Studied by Intracellular Recordings in Awake Marmosets.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Modeling and MEG evidence of early consonance processing in auditory cortex.PLoS computational biology · 2019Article
- Differential cell-type dependent brain state modulations of sensory representations in the non-lemniscal mouse inferior colliculus.Communications biology · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
A key computational principle for encoding time-varying signals in auditory and somatosensory cortices of monkeys is the opponent model of rate coding by two distinct populations of neurons. However, the subthreshold mechanisms that give rise to this computation have not been revealed. Because the rate-coding neurons are only observed in awake conditions, it is especially challenging to probe their underlying cellular mechanisms. Using a novel intracellular recording technique that we developed in awake marmosets, we found that the two types of rate-coding neurons in auditory cortex exhibited distinct subthreshold responses. While the positive-monotonic neurons (monotonically increasing firing rate with increasing stimulus repetition frequency) displayed sustained depolarization at high repetition frequency, the negative-monotonic neurons (opposite trend) instead exhibited hyperpolarization at high repetition frequency but sustained depolarization at low repetition frequency. The combination of excitatory and inhibitory subthreshold events allows the cortex to represent time-varying signals through these two opponent neuronal populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.