Sertraline-induced increase in VEGF brain levels and its activity in cryptococcal meningitis.

Pierre Loulergue, Olivier Mir, Pierre Rocheteau, Fabrice Chrétien, Raphaël Gaillard

Abstract readLetterComment

In one paragraph

Article in The Lancet. Infectious diseases, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

Platelets and mast cells promote pathogenic eosinophil recruitment during invasive fungal infection via the 5-HIAA-GPR35 ligand-receptor system.Immunity · 2023
Article
Assessment of peripheral biomarkers potentially involved in episodic and chronic migraine: a case-control study with a focus on NGF, BDNF, VEGF, and PGE2.The journal of headache and pain · 2022
Article

4 · The record

Corrections and comments

Comment on
Efficacy of adjunctive sertraline for the treatment of HIV-associated cryptococcal meningitis: an open-label dose-ranging study.2016

5 · Who and what money

Authors and funding

5 authors.

Pierre LoulergueCochin Teaching Hospital, Assistance Publique-Hôpitaux de Paris, 75014 Paris, France. Electronic address: pierre.loulergue@aphp.fr.

Olivier MirGustave Roussy Cancer Campus, Villejuif, France.

Pierre RocheteauHuman Histopathology and Animal Models, Infection and Epidemiology Department, Institut Pasteur, Paris, France.

Fabrice ChrétienHuman Histopathology and Animal Models, Infection and Epidemiology Department, Institut Pasteur, Paris, France.

Raphaël GaillardService Hospitalo Universitaire, Centre Hospitalier Sainte-Anne, Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Meningitis, CryptococcalSertralineBrainCryptococcosisHumansVascular Endothelial Growth Factor ASertralineVascular Endothelial Growth Factor A

Identifiers

PMID27477978

DOI10.1016/S1473-3099(16)30147-5

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.