ArticleNature communications2016
Ascarosides coordinate the dispersal of a plant-parasitic nematode with the metamorphosis of its vector beetle.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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Who cites it
46 citing papers in PubMed, 107 citations in OpenAlex.
- Pinewood Nematodes Manipulate Locomotion of the Vector Beetle Through ATP1-Driven Energy Metabolism.Integrative zoology · 2026Article
- Plant pathogenic nematode exosomes remodel vector tracheae to enhance pathogen transmission.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- A Cold Stress-Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Cyclohexyl acetate functions like a volatile sex pheromone mimic in Caenorhabditis nematodes.BMC biology · 2026Article
- Nutrient State-Dependent Ascarosides and Nematode Immune Response Limit the Predation ofMicroorganisms · 2025Article
- A male-derived volatile sex pheromone inbioRxiv : the preprint server for biology · 2025Article
- The Threshold and Lag Effects of Temperature on Pine Wilt Disease Show Significant Spatial Heterogeneity.Insects · 2025Article
- Significant Differences in the Effects of Pine Wilt Disease Invasion on Plant Diversity in Natural and Planted Forests.Insects · 2025Article
- Distribution of Trichostrongylus colubriformis on common pasture grasses and legumes from the Midwestern United States.PloS one · 2025Article
- Article
- Detection Methods for Pine Wilt Disease: A Comprehensive Review.Plants (Basel, Switzerland) · 2024Review
- Ascarosides and Symbiotic Bacteria of Entomopathogenic Nematodes Regulate Host Immune Response inInsects · 2024Article
- The nematode-trapping fungus Arthrobotrys oligospora detects prey pheromones via G protein-coupled receptors.Nature microbiology · 2024Article
- Physiological Measurements and Transcriptomics Reveal the Fitness Costs ofInternational journal of molecular sciences · 2024Article
- A near-complete genome assembly of Monochamus alternatus a major vector beetle of pinewood nematode.Scientific data · 2024Article
- Hypoxia-induced tracheal elasticity in vector beetle facilitates the loading of pinewood nematode.eLife · 2023Article
- Adaptive Reproductive Strategies of an EctoparasitoidInsects · 2023Article
- Nematode Pheromones: Structures and Functions.Molecules (Basel, Switzerland) · 2023Review
- How didFrontiers in physiology · 2023Article
- Microhabitat Governs the Microbiota of the Pinewood Nematode and Its Vector Beetle: Implication for the Prevalence of Pine Wilt Disease.Microbiology spectrum · 2022Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Insect vectors are required for the transmission of many species of parasitic nematodes, but the mechanisms by which the vectors and nematodes coordinate their life cycles are poorly understood. Here, we report that ascarosides, an evolutionarily conserved family of nematode pheromones, are produced not only by a plant-parasitic nematode, but also by its vector beetle. The pinewood nematode and its vector beetle cause pine wilt disease, which threatens forest ecosystems world-wide. Ascarosides secreted by the dispersal third-stage nematode LIII larvae promote beetle pupation by inducing ecdysone production in the beetle and up-regulating ecdysone-dependent gene expression. Once the beetle develops into the adult stage, it secretes ascarosides that attract the dispersal fourth-stage nematode LIV larvae, potentially facilitating their movement into the beetle trachea for transport to the next pine tree. These results demonstrate that ascarosides play a key role in the survival and spread of pine wilt disease.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.