Evidence map›Paper›PMID 27477611›Full record

ArticleJournal of medical primatology2016

Genetic diversity of Klebsiella pneumoniae isolates during an outbreak in a non-human primate research colony.

Alfonso S Gozalo, William R Elkins, Lynn E Lambert, Frida Stock, Marvin L Thomas, Ruth A Woodward

Abstract read
In one paragraph

Article in Journal of medical primatology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Bilateral Perinephric Pseudocysts in an Owl Monkey.Journal of medical primatology · 2025
    Article
  3. Review
  4. Review
  5. Antibiotic resistance and virulence profile ofJournal of advanced veterinary and animal research · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alfonso S GozaloComparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
William R ElkinsComparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Lynn E LambertLaboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Frida StockDepartment of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, MD, USA.
Marvin L ThomasDivision of Veterinary Resources, National Institutes of Health, Bethesda, MD, USA.
Ruth A WoodwardResearch Animal Medicine Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

Funding

Comparative Medicine Infectious Diseases- BethesdaZIGAI001047 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI ELKINS, WILLIAM · 2009 to 2025
$535.6M
Intramural NIH HHS Z99 AI999999
6 · The paper itself

Abstract

backgroundKlebsiella pneumoniae can be a serious pathogen in non-human primates, particularly Neotropical monkeys.

methodsDuring a K. pneumoniae outbreak in an owl monkey research colony, 13 K. pneumoniae isolates were DNA fingerprinted by automated repetitive extragenic palindromic-polymerase chain reaction and the profiles compared to isolates obtained from other non-human primate species during the same time period and isolates from previous outbreaks.

resultsEleven different types of K. pneumoniae were circulating in the owl monkey colony at the time of the outbreak. When comparing owl monkey isolates relatedness to previous colony outbreak isolates and squirrel monkey and capuchin monkey isolates, all were different.

conclusionsThese results agree with recent reports where K. pneumoniae nosocomial isolates in hospital settings can have high genetic diversity, and multiple strains can be circulating simultaneously. This potential genetic diversity should be considered when designing strategies for controlling K. pneumoniae outbreaks in captive non-human primate colonies.

Indexed as

AotidaeDisease OutbreaksGenetic VariationAnimalsAnimals, LaboratoryFemaleKlebsiella InfectionsKlebsiella pneumoniaeMaleMonkey DiseasesAotus nancymaiautomated repetitive extragenic palindromic-polymerase chain reactionCebidaeDNA fingerprintingKlebsiellosisowl monkeyrep-PCR

Identifiers

PMID27477611
PMCPMC5288377

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.