Evidence map›Paper›PMID 27477451›Full record

ArticleInfection control and hospital epidemiology2016

Assessment of Self-Contamination During Removal of Personal Protective Equipment for Ebola Patient Care.

Lisa M Casanova, Lisa J Teal, Emily E Sickbert-Bennett, Deverick J Anderson, Daniel J Sexton, William A Rutala, David J Weber, CDC Prevention Epicenters Program

Abstract read
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In one paragraph

Article in Infection control and hospital epidemiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 71 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Trial
  5. Review
  6. Review
  7. Article
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  12. Dental services during the COVID-19 pandemic: A tertiary care hospital experience.Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry · 2020
    Review
  13. Article
  14. Review
  15. Design Strategies for Biocontainment Units to Reduce Risk During Doffing of High-level Personal Protective Equipment.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  16. Effect of Glove Decontamination on Bacterial Contamination of Healthcare Personnel Hands.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  17. Healthcare Workers' Strategies for Doffing Personal Protective Equipment.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  18. Development and Comparison of Complementary Methods to Study Potential Skin and Inhalational Exposure to Pathogens During Personal Protective Equipment Doffing.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2019
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Lisa M Casanova1Division of Environmental Health,School of Public Health,Georgia State University,Atlanta,Georgia.
Lisa J Teal2Hospital Epidemiology,University of North Carolina Healthcare,Chapel Hill,North Carolina.
Emily E Sickbert-Bennett2Hospital Epidemiology,University of North Carolina Healthcare,Chapel Hill,North Carolina.
Deverick J Anderson3Division of Infectious Diseases,Duke University Medical Center,Durham,North Carolina.
Daniel J Sexton3Division of Infectious Diseases,Duke University Medical Center,Durham,North Carolina.
William A Rutala2Hospital Epidemiology,University of North Carolina Healthcare,Chapel Hill,North Carolina.
David J Weber2Hospital Epidemiology,University of North Carolina Healthcare,Chapel Hill,North Carolina.
CDC Prevention Epicenters Program
University of North Carolina Hospitals · USDuke Medical Center · USGeorgia State University · US

Funding

NCEZID CDC HHS U54 CK000164
6 · The paper itself

Abstract

OBJECTIVE Ebola virus disease (EVD) places healthcare personnel (HCP) at high risk for infection during patient care, and personal protective equipment (PPE) is critical. Protocols for EVD PPE doffing have not been validated for prevention of viral self-contamination. Using surrogate viruses (non-enveloped MS2 and enveloped Φ6), we assessed self-contamination of skin and clothes when trained HCP doffed EVD PPE using a standardized protocol. METHODS A total of 15 HCP donned EVD PPE for this study. Virus was applied to PPE, and a trained monitor guided them through the doffing protocol. Of the 15 participants, 10 used alcohol-based hand rub (ABHR) for glove and hand hygiene and 5 used hypochlorite for glove hygiene and ABHR for hand hygiene. Inner gloves, hands, face, and scrubs were sampled after doffing. RESULTS After doffing, MS2 virus was detected on the inner glove worn on the dominant hand for 8 of 15 participants, on the non-dominant inner glove for 6 of 15 participants, and on scrubs for 2 of 15 participants. All MS2 on inner gloves was observed when ABHR was used for glove hygiene; none was observed when hypochlorite was used. When using hypochlorite for glove hygiene, 1 participant had MS2 on hands, and 1 had MS2 on scrubs. CONCLUSIONS A structured doffing protocol using a trained monitor and ABHR protects against enveloped virus self-contamination. Non-enveloped virus (MS2) contamination was detected on inner gloves, possibly due to higher resistance to ABHR. Doffing protocols protective against all viruses need to incorporate highly effective glove and hand hygiene agents. Infect Control Hosp Epidemiol 2016;1-6.

Indexed as

BacteriophagesCross InfectionEbolavirusGloves, ProtectiveHand HygieneHemorrhagic Fever, EbolaHumansInfection Control PractitionersInfectious Disease Transmission, Patient-to-ProfessionalNursesPersonal Protective EquipmentPhysicians

Identifiers

PMID27477451
OpenAlexW2489108682

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.