Evidence map›Paper›PMID 27477117›Full record

ArticleJournal of mass spectrometry : JMS2016

Travelling-wave ion mobility mass spectrometry and negative ion fragmentation of hybrid and complex N-glycans.

David J Harvey, Charlotte A Scarff, Matthew Edgeworth, Kevin Pagel, Konstantinos Thalassinos, Weston B Struwe, Max Crispin, James H Scrivens

Open access · greenAbstract read
In one paragraph

Article in Journal of mass spectrometry : JMS, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Identification ofThe Analyst · 2022
    Article
  6. Article
  7. Article
  8. State-of-the-Art Glycomics Technologies in Glycobiotechnology.Advances in biochemical engineering/biotechnology · 2021
    Article
  9. Article
  10. Review
  11. Advancing Solutions to the Carbohydrate Sequencing Challenge.Journal of the American Chemical Society · 2019
    Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

David J HarveyOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK. david.harvey@bioch.ox.ac.uk.
Charlotte A ScarffDepartment of Biological Sciences, University of Warwick, Coventry, CV47AL, UK.
Matthew EdgeworthDepartment of Biological Sciences, University of Warwick, Coventry, CV47AL, UK.
Kevin PagelInstitute of Chemistry and Biochemistry, Freie Universität Berlin, Takustrasse. 3, 14159, Berlin, Germany.
Konstantinos ThalassinosInstitute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck College, University of London, London, WC1E 7HX, UK.
Weston B StruweOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
Max CrispinOxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, UK.
James H ScrivensDepartment of Biological Sciences, University of Warwick, Coventry, CV47AL, UK.
University of Warwick · GBUniversity of Oxford · GBFreie Universität Berlin · DEInstitute of Structural and Molecular Biology · GBScience Oxford · GB

Funding

Support Component D/Vaccine Discovery, Concept to ClinicUM1AI100663 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI BAROUCH, DAN H. · 2012 to 2018
$131.5M
NIAID NIH HHS UM1 AI100663
6 · The paper itself

Abstract

Nitrogen collisional cross sections (CCSs) of hybrid and complex glycans released from the glycoproteins IgG, gp120 (from human immunodeficiency virus), ovalbumin, α1-acid glycoprotein and thyroglobulin were measured with a travelling-wave ion mobility mass spectrometer using dextran as the calibrant. The utility of this instrument for isomer separation was also investigated. Some isomers, such as Man

Indexed as

FucoseGlycoproteinsIonsIsomerismMannoseMass SpectrometryMovementPeptide FragmentsPolysaccharidesFucoseGlycoproteinsIonsMannosePeptide FragmentsPolysaccharidesCIDcomplex N-glycanshybrid N-glycansisomersnegative ionN-linked carbohydratesT-wave ion mobility

Identifiers

PMID27477117
PMCPMC5150983
OpenAlexW2493124561

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.