Evidence map›Paper›PMID 27476878›Full record

ArticleChemical communications (Cambridge, England)2016

Light-controlled active release of photocaged ciprofloxacin for lipopolysaccharide-targeted drug delivery using dendrimer conjugates.

Pamela T Wong, Shengzhuang Tang, Jhindan Mukherjee, Kenny Tang, Kristina Gam, Danielle Isham, Claire Murat, Rachel Sun, James R Baker, Seok Ki Choi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Photomodulation Approaches to Overcome Antimicrobial Resistance.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Green Algae as a Drug Delivery System for the Controlled Release of Antibiotics.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020
    Article
  5. Article
  6. Article
  7. Review
  8. Antimicrobial Polymers: The Potential Replacement of Existing Antibiotics?International journal of molecular sciences · 2019
    Review
  9. UCN-SiORSC advances · 2018
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pamela T WongMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu and Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
Shengzhuang TangMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu and Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
Jhindan MukherjeeMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu and Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
Kenny TangMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu.
Kristina GamMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu.
Danielle IshamMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu.
Claire MuratMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu.
Rachel SunMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu.
James R BakerMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu and Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
Seok Ki ChoiMichigan Nanotechnology Institute for Medicine and Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA. ptw@umich.edu skchoi@umich.edu and Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.

Funding

CUTTING EDGE LINEAGE TRACKING OF TUMOR-EDUCATED IMMUNE CELLSR21CA191428 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KRUMMEL, MATTHEW F · 2015 to 2016
$391k
NCI NIH HHS R21 CA191428
6 · The paper itself

Abstract

We report an active delivery mechanism targeted specifically to Gram(-) bacteria based on the photochemical release of photocaged ciprofloxacin carried by a cell wall-targeted dendrimer nanoconjugate.

Indexed as

Anti-Bacterial AgentsCiprofloxacinDendrimersDrug Delivery SystemsEscherichia coliGram-Negative BacteriaLigandsLipopolysaccharidesNanoconjugatesPolyaminesPolymyxin BUltraviolet RaysAnti-Bacterial AgentsCiprofloxacinDendrimersLigandsLipopolysaccharidesNanoconjugatesPoly(amidoamine)PolyaminesPolymyxin B

Identifiers

PMID27476878
PMCPMC4987215

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.