Evidence map›Paper›PMID 27476791›Full record

ReviewImmunobiology2016

Innate and adaptive immunologic functions of complement in the host response to Listeria monocytogenes infection.

Daniel G Calame, Stacey L Mueller-Ortiz, Rick A Wetsel

Open access · greenAbstract readReview
In one paragraph

Review in Immunobiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Transcriptomics in Rare Minnow (Animals : an open access journal from MDPI · 2023
    Article
  2. Article
  3. An Immunomodulatory Transcriptional Signature Associated With PersistentFrontiers in cellular and infection microbiology · 2021
    Article
  4. Article
  5. Human Short Peptidoglycan Recognition Protein PGLYRP1/Tag-7/PGRP-S InhibitsFrontiers in cellular and infection microbiology · 2020
    Article
  6. RespiratoryInternational journal of molecular sciences · 2018
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Case reports in rheumatology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Daniel G CalameThe Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, United States; University of Texas McGovern Medical School at Houston, The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX 77030, United States.
Stacey L Mueller-OrtizThe Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, United States.
Rick A WetselThe Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, United States; Department of Biochemistry and Molecular Biology, University of Texas McGovern Medical School at Houston, Houston, TX 77030, United States. Electronic address: Rick.A.Wetsel@uth.tmc.edu.
Brown Foundation · US

Funding

MURINE COMPLEMENT C5 DEFICIENCY--MOLECULAR BASISR01AI025011 · NIAID · WASHINGTON UNIVERSITY · PI WETSEL, RICK A. · 1987 to 2017
$4.6M
NIAID NIH HHS R01 AI025011
6 · The paper itself

Abstract

Listeria monocytogenes is a leading cause of foodborne-illness associated mortality that has attracted considerable attention in recent years due to several significant outbreaks. It has also served as a model organism for the study of intracellular pathogens. For these reasons the host response to L. monocytogenes has long been the subject of investigation. A potent innate and adaptive immune response is required for containment and clearance of L. monocytogenes. However, some elements of this response, such as type 1 interferons, can be detrimental to the host. Recent studies have revealed novel functions for the complement system, an ancient arm of innate immunity, in this process. Here we review the role of complement in the host response to L. monocytogenes.

Indexed as

Adaptive ImmunityAnimalsComplement ActivationComplement System ProteinsHost-Pathogen InteractionsHumansImmunity, InnateInterferon Type IListeria monocytogenesListeriosisComplement System ProteinsInterferon Type IComplementFoodborne illnessImmune responseListeria monocytogenes

Identifiers

PMID27476791
PMCPMC5345573
OpenAlexW2478161470

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.