Evidence map›Paper›PMID 27475258›Full record

Trial reportHeart, lung & circulation2017

Impact of Insurance Type on Initial Rejection Post Heart Transplant.

Khadijah Breathett, Shannon Willis, Randi E Foraker, Sakima Smith

Abstract readClinical Trial
In one paragraph

Trial report in Heart, lung & circulation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Increased disparities in waitlist and post-heart transplantation outcomes according to socioeconomic status with the new heart transplant allocation system.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2024
    Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Khadijah BreathettDivision of Cardiology, University of Colorado Anschutz Medical Center, Aurora, Colorado. Electronic address: Khadijah.breathett@ucdenver.edu.
Shannon WillisDepartment of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio.
Randi E ForakerDivision of Epidemiology, College of Public Health, The Ohio State University, Columbus, Ohio.
Sakima SmithDivision of Cardiology, The Ohio State University Wexner Medical Center, Columbus, Ohio.
The Ohio State University Wexner Medical Center · USThe Ohio State University · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral TrainingT32HL116276 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ECKEL, ROBERT H · 2014 to 2018
$1.2M
NHLBI NIH HHS T32 HL116276
6 · The paper itself

Abstract

backgroundHeart transplantation allocation is often restricted from patients with low socioeconomic status (SES) due to concern for worse outcomes. We hypothesised that comorbidities would have a greater impact on risk of severe rejection post-orthotopic heart transplant than would Medicaid insurance and Median Household Income (MHI).

methodsA retrospective study of 171 patients who underwent orthotopic heart transplant between 7/1999-11/2013 at our facility were followed until 9/2014 for rejection hospitalisations or death. Survival and multivariable analyses with adjustment for age, race, and gender were performed to estimate the risk of severe cellular rejection, ≥2r (hazard ratio [HR], 95% confidence interval [CI]).

resultsEighteen per cent of patients had Medicaid, and 72% of patients had low or medium MHI. Severe rejection occurred in 23% of patients. In the univariable analysis, Medicaid and diabetes were associated with increased risk of rejection while age >60 years, Caucasian race, and male sex were associated with reduced risk [Medicaid 2.32(1.20,4.51), diabetes 2.49(1.09,5.69), age 0.41(0.20,0.84), Caucasian 0.44(0.21,0.93), male 0.49(0.26,0.92)]. Median Household Income had no correlation [MHI 0.79(0.51,1.23)]. In the multivariable adjusted model, Medicaid was not associated with rejection [1.65(0.79,3.41)]; diabetes was strongly associated with risk of severe rejection [3.9(1.59,9.39)], and age >60 years was associated with risk reduction [0.42(0.20,0.82)].

conclusionsMedicaid insurance and MHI were not associated with increased risk of severe cellular rejection requiring hospitalisation post-orthotopic heart transplant in the adjusted model. Rather the presence of diabetes and age ≤60 years were associated with increased risk.

Indexed as

Graft RejectionHeart TransplantationInsuranceMedicaidAdolescentAdultAgedAge FactorsFemaleHumansMaleMiddle AgedRisk FactorsSocioeconomic FactorsUnited StatesDiabetesOutcomesSocioeconomic status

Identifiers

PMID27475258
PMCPMC5195871
OpenAlexW2492298304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.