ArticleMolecular plant pathology2017
Different waves of effector genes with contrasted genomic location are expressed by Leptosphaeria maculans during cotyledon and stem colonization of oilseed rape.
Article in Molecular plant pathology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 63 citations in OpenAlex.
- Conserved 'Late' Effector Genes From Leptosphaeria maculans Inducing Gene-For-Gene Quantitative Resistance in Brassica napus Semi-Winter Genotypes.Molecular plant pathology · 2026Article
- Spatial and single-cell transcriptomics capture two distinct cell states in soybean defense response toFrontiers in plant science · 2025Article
- Repeat-induced point mutations driving Parastagonospora nodorum genomic diversity are balanced by selection against non-synonymous mutations.Communications biology · 2024Article
- To be or not to be a nonhost species: A case study of the Leptosphaeria maculans and Brassica carinata interaction.Environmental microbiology reports · 2024Article
- Breeding and management of major resistance genes to stem canker/blackleg in Brassica crops.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- Host Recognition and Specific Infection ofJournal of fungi (Basel, Switzerland) · 2023Article
- Epigenetic regulation of nuclear processes in fungal plant pathogens.PLoS pathogens · 2023Review
- The SET domain protein PsKMT3 regulates histone H3K36 trimethylation and modulates effector gene expression in the soybean pathogen Phytophthora sojae.Molecular plant pathology · 2023Article
- Article
- "Late" effectors fromPlant direct · 2022Article
- Infection Strategies and Pathogenicity of Biotrophic Plant Fungal Pathogens.Frontiers in microbiology · 2022Review
- A new avirulence gene of Leptosphaeria maculans, AvrLm14, identifies a resistance source in American broccoli (Brassica oleracea) genotypes.Molecular plant pathology · 2021Article
- An automated and combinative method for the predictive ranking of candidate effector proteins of fungal plant pathogens.Scientific reports · 2021Article
- A gene-for-gene interaction involving a 'late' effector contributes to quantitative resistance to the stem canker disease in Brassica napus.The New phytologist · 2021Article
- Genome-wide mapping of histone modifications during axenic growth in two species of Leptosphaeria maculans showing contrasting genomic organization.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2021Article
- Tandem DNA repeats contain cis-regulatory sequences that activate biotrophy-specific expression of Magnaporthe effector gene PWL2.Molecular plant pathology · 2021Article
- Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant.BMC biology · 2021Article
- Recent Findings Unravel Genes and Genetic Factors UnderlyingInternational journal of molecular sciences · 2020Review
- Structural specificity in plant-filamentous pathogen interactions.Molecular plant pathology · 2020Review
- Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptosphaeria maculans, the causal agent of stem canker disease, colonizes oilseed rape (Brassica napus) in two stages: a short and early colonization stage corresponding to cotyledon or leaf colonization, and a late colonization stage during which the fungus colonizes systemically and symptomlessly the plant during several months before stem canker appears. To date, the determinants of the late colonization stage are poorly understood; L. maculans may either successfully escape plant defences, leading to stem canker development, or the plant may develop an 'adult-stage' resistance reducing canker incidence. To obtain an insight into these determinants, we performed an RNA-sequencing (RNA-seq) pilot project comparing fungal gene expression in infected cotyledons and in symptomless or necrotic stems. Despite the low fraction of fungal material in infected stems, sufficient fungal transcripts were detected and a large number of fungal genes were expressed, thus validating the feasibility of the approach. Our analysis showed that all avirulence genes previously identified are under-expressed during stem colonization compared with cotyledon colonization. A validation RNA-seq experiment was then performed to investigate the expression of candidate effector genes during systemic colonization. Three hundred and seven 'late' effector candidates, under-expressed in the early colonization stage and over-expressed in the infected stems, were identified. Finally, our analysis revealed a link between the regulation of expression of effectors and their genomic location: the 'late' effector candidates, putatively involved in systemic colonization, are located in gene-rich genomic regions, whereas the 'early' effector genes, over-expressed in the early colonization stage, are located in gene-poor regions of the genome.
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