ArticleMovement disorders : official journal of the Movement Disorder Society2016
Stop-related subthalamic beta activity indexes global motor suppression in Parkinson's disease.
Article in Movement disorders : official journal of the Movement Disorder Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.
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Who cites it
53 citing papers in PubMed, 1 synthesis or guideline pooled it, 122 citations in OpenAlex.
- Pooled it
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- β-Bursting as a Sensitive Neural Marker of Inhibitory Control in Healthy Older Adults: A Linear Mixed-Effects Modeling and Threshold-Free Cluster Approach.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Global Motor System Suppression as the Primary Mechanism of Human Action Stopping: Challenging the Pause-Then-Cancel Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Article
- Precisely-timed outpatient recordings of subcortical local field potentials from wireless streaming-capable deep-brain stimulators: a method and toolbox.Journal of neuroscience methods · 2025Article
- 20 Hz beta stimulation of the subthalamic nucleus improves response inhibition in Parkinson's disease.Brain communications · 2025Article
- Theta and beta power in the subthalamic nucleus responds to conflict across subregions and hemispheres.Brain communications · 2025Article
- Burst estimation through atomic decomposition (BEAD): A toolbox to find oscillatory bursts in brain signals.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Subthalamic control of impulsive actions: insights from deep brain stimulation in Parkinson's disease.Brain : a journal of neurology · 2024Review
- Subthalamic stimulation causally modulates human voluntary decision-making to stay or go.NPJ Parkinson's disease · 2024Article
- Examining motor evidence for the pause-then-cancel model of action-stopping: insights from motor system physiology.Journal of neurophysiology · 2024Article
- Decreased Beta Power and OFC-STN Phase Synchronization during Reactive Stopping in Freely Behaving Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Prefrontal-subthalamic theta signaling mediates delayed responses during conflict processing.Progress in neurobiology · 2024Article
- Examining motor evidence for the pause-then-cancel model of action-stopping: Insights from motor system physiology.bioRxiv : the preprint server for biology · 2024Article
- Beta-triggered adaptive deep brain stimulation during reaching movement in Parkinson's disease.Brain : a journal of neurology · 2023Article
- Neural mechanisms of domain-general inhibitory control.Trends in cognitive sciences · 2023Review
- Uncovering the neurophysiology of mood, motivation and behavioral symptoms in Parkinson's disease through intracranial recordings.NPJ Parkinson's disease · 2023Review
- Multi-scale and cross-dimensional TMS mapping: A proof of principle in patients with Parkinson's disease and deep brain stimulation.Frontiers in neuroscience · 2023Article
- Individual differences in beta-band oscillations predict motor-inhibitory control.Frontiers in neuroscience · 2023Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundRapid action stopping leads to global motor suppression. This is shown by studies using transcranial magnetic stimulation to measure corticospinal excitability of task-unrelated effectors (e.g., from the hand during speech stopping). We hypothesize that this global suppression relates to the STN of the basal ganglia. Several STN local field potential studies in PD patients have shown increased ß-band power during successful stopping.
objectivesHere, we aimed to test whether this STN ß-band activity indexes global motor suppression measured by transcranial magnetic stimulation.
methodsWe studied 9 medicated PD patients (age, 47-67 years; mean, 55.8; 3 female) who were implanted with STN-DBS electrodes. Participants performed a vocal stop-signal task (i.e., they had to occasionally stop a vocal response) while we simultaneously recorded local field potentials from right STN and delivered transcranial magnetic stimulation to primary motor cortex to measure corticospinal excitability from a task-unrelated hand muscle (first dorsal interosseous).
resultsReplicating previous results, STN ß-band power was increased (P < 0.005) and corticospinal excitability was reduced (P = 0.024; global motor suppression) during successful stopping. As hypothesized, global motor suppression was greater for successful stop trials with higher STN ß-power (median split: P = 0.043), which was further evident in a negative correlation between single-trial STN ß-power and corticospinal excitability (mean, r = -0.176; P = 0.011).
conclusionThese findings link stopping-related global motor suppression to STN ß-band activity through simultaneous recordings of STN and corticospinal excitability. The results support models of basal ganglia function that propose the STN has broad motor suppressive effects. © 2016 International Parkinson and Movement Disorder Society.
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