Reduced respiratory neural activity elicits a long-lasting decrease in the CO

N A Baertsch, T L Baker

Abstract read

In one paragraph

Article in Experimental neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

Circuit Mechanisms Underlying the Contribution of Leptin Receptor-Expressing Neurons in the Nucleus Tractus Solitarius to Ventilatory Homeostasis.Neuroscience bulletin · 2026
Article
The level of carbon dioxide is the determinant of successful noninvasive ventilation pressure titration in patients with nonhypercapnic primary central sleep apnea: a case report.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
Article
Retinoic acid receptor alpha activation is necessary and sufficient for plasticity induced by recurrent central apnea.Journal of applied physiology (Bethesda, Md. : 1985) · 2021
Article
Competing mechanisms of plasticity impair compensatory responses to repetitive apnoea.The Journal of physiology · 2019
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

N A BaertschDepartment of Comparative Biosciences, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA.

T L BakerDepartment of Comparative Biosciences, University of Wisconsin-Madison, 2015 Linden Drive, Madison, WI 53706, USA. Electronic address: bakert@svm.vetmed.wisc.edu.

Funding

Mechanisms of inactivity-induced respiratory plasticityR01HL105511 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI BAKER, TRACY L · 2011 to 2020

$3.3M

NHLBI NIH HHS R01 HL105511

6 · The paper itself

Abstract

Two critical parameters that influence breathing stability are the levels of arterial pCO

Indexed as

Action PotentialsAnalysis of VarianceAnesthesiaAnimalsApneaBlood Gas AnalysisBlood PressureCarbon DioxideDisease Models, AnimalMaleMotor NeuronsPhrenic NerveRatsRats, Sprague-DawleySensory ThresholdsTime FactorsCarbon DioxideApneaApneic thresholdCentral sleep apneaChemoreflexControl of breathingCSAiPMFPhrenicPlasticityReduced respiratory neural activityRespiratory motor neurons

Identifiers

PMID27474512

DOI10.1016/j.expneurol.2016.07.020

PMCPMC5683180

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.