ReviewPerspectives on psychological science : a journal of the Association for Psychological Science2016
A Stage Model of Stress and Disease.
Review in Perspectives on psychological science : a journal of the Association for Psychological Science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04339790 (Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers), which is not on this map. Cited by 217 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
Who cites it
217 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- The influence of stress on the neural underpinnings of disinhibited eating: a systematic review and future directions for research.Reviews in endocrine & metabolic disorders · 2023Pooled it
- Glucocorticoid resistance and β2-adrenergic receptor signaling pathways promote peripheral pro-inflammatory conditions associated with chronic psychological stress: A systematic review across species.Neuroscience and biobehavioral reviews · 2021Pooled it
- Efficacy of probiotics on stress in healthy volunteers: A systematic review and meta-analysis based on randomized controlled trials.Brain and behavior · 2020Pooled it
- Examining the Impact of Acute Exercise and Arousal Reappraisal on Stressor-Evoked Psychological and Cardiovascular Responses.Psychophysiology · 2026Trial
- Story-Telling Attention-Refocusing (STAR) intervention to alleviate acute stress in parents of infants in the NICU.Journal of neonatal-perinatal medicine · 2025Trial
- The Selah trial: A preference-based partially randomized waitlist control study of three stress management interventions.Translational behavioral medicine · 2025Trial
- The moderating role of diabetes distress on the effect of a randomized eHealth intervention on glycemic control in Black adolescents with type 1 diabetes.Journal of pediatric psychology · 2024Trial
- Do financial constraint and perceived stress modify the effects of food tax schemes on food purchases: moderation analyses in a virtual supermarket experiment.Public health nutrition · 2024Trial
- Reducing neuroendocrine psychosocial stress response through socio-emotional dyadic but not mindfulness online training.Frontiers in endocrinology · 2024Trial
- Mental health trajectories after juridical divorce: Does personality matter?Journal of personality · 2023Trial
- Mindfulness-based stress reduction increases stimulated IL-6 production among lonely older adults: A randomized controlled trial.Brain, behavior, and immunity · 2022Trial
- The Effects of Acceptance and Commitment Therapy (ACT) Intervention on Inflammation and Stress Biomarkers: a Randomized Controlled Trial.International journal of behavioral medicine · 2020Trial
- Stress-induced IL-6 response patterns amplify the link between daily negative affect and later depressive symptoms during bereavement.Brain, behavior, and immunity · 2026Article
- Perceived Stress and Depressive Symptoms in Urban Chinese Women: The Buffering and Exacerbating Roles of Marital Quality.Healthcare (Basel, Switzerland) · 2026Article
- The effect of psychological stress on masticatory muscle electromyography-a scoping review.Journal of oral & facial pain and headache · 2026Article
- Does Aerobic Capacity Protect Against Stress? Insights From Two Stress-Induction Paradigms.Psychophysiology · 2026Article
- Validating the stress and adversity inventory for adults (Adult STRAIN) among urban middle-aged and older African Americans.Journal of health psychology · 2026Article
- Impact of different stress paradigms on irritable bowel syndrome: Evidence from clinical and animal studies.The Journal of international medical research · 2026Review
- Electrocardiogram-Based Mental Stress Detection Amid Everyday Activities Using Machine Learning: Model Development and Validation Study.Journal of medical Internet research · 2026Article
- The Metabolomic Signature of Stressful Life Events.medRxiv : the preprint server for health sciences · 2026Article
157 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
In this article, we argued that the term stress has served as a valuable heuristic, helping researchers to integrate traditions that illuminate different stages of the process linking stressful life events to disease. We provided a short history of three traditions in the study of stress: the epidemiological, psychological, and biological. The epidemiological tradition focuses on defining which circumstances and experiences are deemed stressful on the basis of consensual agreement that they constitute threats to social or physical well-being. The psychological tradition focuses on individuals' perceptions of the stress presented by life events on the basis of their appraisals of the threats posed and the availability of effective coping resources. The biological tradition focuses on brain-based perturbations of physiological systems that are otherwise essential for normal homeostatic regulation and metabolic control. The foci of these three traditions have informed elements of a stage model of disease, wherein events appraised as stressful are viewed as triggering affective states that in turn engender behavioral and biological responses having possible downstream implications for disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.