ArticleThe Journal of allergy and clinical immunology2016
Rhinovirus and serum IgE are associated with acute asthma exacerbation severity in children.
Registry-linked trialOpen access · bronzeAbstract readLetter
In one paragraph
Article in The Journal of allergy and clinical immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04670627 (Investigation of Molecular Biomarkers Associated With Occurrence of Seasonal Allergic Rhinitis), which is not on this map. Cited by 33 papers.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation of Molecular Biomarkers Associated With Occurrence of Seasonal Allergic Rhinitis (AR) In and Out of Active Allergy Season
Who cites it
33 citing papers in PubMed, 57 citations in OpenAlex.
- The usual suspects: Respiratory syncytial virus and rhinovirus drive asthma development and exacerbation.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025Review
- Review
- Biomarkers of type 2 and non-type 2 inflammation in asthma exacerbations.Central-European journal of immunology · 2024Article
- Histamine-releasing factor in severe asthma and rhinovirus-associated asthma exacerbation.The Journal of allergy and clinical immunology · 2023Article
- Review
- Novel potential treatable traits in asthma: Where is the research taking us?The journal of allergy and clinical immunology. Global · 2022Review
- Immunoglobulin E-Dependent Activation of Immune Cells in Rhinovirus-Induced Asthma Exacerbation.Frontiers in allergy · 2022Article
- Innate Immune Responses by Respiratory Viruses, Including Rhinovirus, During Asthma Exacerbation.Frontiers in immunology · 2022Review
- The effect of COVID-19 on patients with chronic spontaneous urticaria treated with omalizumab and antihistamines: A cross-sectional, comparative study.Journal of cosmetic dermatology · 2021Article
- Rhinovirus and asthma: Challenges and opportunities.Reviews in medical virology · 2021Review
- Immunological Aspects Related to Viral Infections in Severe Asthma and the Role of Omalizumab.Biomedicines · 2021Review
- Prevention of Asthma: Targets for Intervention.Chest · 2020Review
- Human TThe Journal of allergy and clinical immunology · 2020Article
- Risk factors for intensive care admission in children with severe acute asthma in the Netherlands: a prospective multicentre study.ERJ open research · 2020Article
- Evolving concepts in how viruses impact asthma: A Work Group Report of the Microbes in Allergy Committee of the American Academy of Allergy, Asthma & Immunology.The Journal of allergy and clinical immunology · 2020Article
- Mimicking Antigen-Driven Asthma in Rodent Models-How Close Can We Get?Frontiers in immunology · 2020Review
- Respiratory pathogens and clinical outcomes in children with an asthma exacerbation: A systematic review.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2019Review
- Beyond Respiratory Syncytial Virus and Rhinovirus in the Pathogenesis and Exacerbation of Asthma: The Role of Metapneumovirus, Bocavirus and Influenza Virus.Immunology and allergy clinics of North America · 2019Review
- Preventing the development of asthma: stopping the allergic march.Current opinion in allergy and clinical immunology · 2019Review
- New insights into the utility of omalizumab.The Journal of allergy and clinical immunology · 2019Article
Corrections and comments
- Commented on by
- Commented on byReply.2017
Authors and funding
11 authors at 4 institutions in 1 country.
David B KantorDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston Children's Hospital, Boston, Mass; Department of Anaesthesia, Harvard Medical School, Boston, Mass.
Nicole StenquistDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston Children's Hospital, Boston, Mass.
Molly C McDonaldClinical Research Center, Boston Children's Hospital, Boston, Mass.
Blake J SchultzDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston Children's Hospital, Boston, Mass.
Marissa HauptmanDivision of General Pediatrics, Boston Children's Hospital, Boston, Mass; Region 1 New England Pediatric Environmental Health Specialty Unit, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.
Craig D SmallwoodDepartment of Anesthesiology, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston Children's Hospital, Boston, Mass.
Kyle A NelsonDepartment of Pediatrics, Harvard Medical School, Boston, Mass; Division of Pediatric Emergency Medicine, Boston Children's Hospital, Boston, Mass.
Matthew S PerzanowskiDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY.
Elizabeth C MatsuiDivision of Pediatric Allergy and Immunology, Johns Hopkins University School of Medicine, Baltimore, Md.
Wanda PhipatanakulDepartment of Pediatrics, Harvard Medical School, Boston, Mass; Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass. Electronic address: wanda.phipatanakul@childrens.harvard.edu.
Joel N HirschhornDivision of Endocrinology, Boston Children's Hospital, Boston, Mass; Program in Medical & Population Genetics, Broad Institute of Harvard & MIT, Cambridge, Mass; Department of Genetics, Harvard Medical School, Boston, Mass. Electronic address: joelh@broadinstitute.org.
Boston Children's Hospital · USHarvard University · USColumbia University · USJohns Hopkins University · US
Funding
Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2MTrue Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7MControlling and preventing Asthma progression and Severity in Kids (CASK)U01AI126614 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2016 to 2023
$21.0MPediatric Critical Care Scientist Development ProgramK12HD047349 · NICHD · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI HEATHER T. KEENAN, Kevin M Watt · 2004 to 2026
$17.0MPEDIATRIC ENVIRONMENTAL HEALTH SPECIALTY UNITS (PEHSU) PROGRAMU61TS000118 · TS · ASSOCIATION/OCCUPATIONAL & ENVIR CLINICS · PI KIRKLAND, KATHERINE HAYES · 2009 to 2013
$9.2MSICAS- Diversity SupplementU01AI110397 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2015 to 2020
$8.8MMouse Allergen and Asthma Intervention TrialU01AI083238 · NIAID · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2010 to 2014
$7.9MAsthmaNet: Brigham and Women's Hospital & Children's Hospital BostonU10HL098102 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI ISRAEL, ELLIOT, PHIPATANAKUL, WANDA · 2009 to 2015
$5.5MRESEARCH TRAINING IN PEDIATRIC EMERGENCY MEDICINET32HD040128 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI Kenneth D. Mandl · 2001 to 2026
$5.0MALLERGENS IN INNER-CITY SCHOOLS AND CHILDHOOD ASTHMAR01AI073964 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2008 to 2012
$4.6MEnvironmental Control as Add-on Therapy in Urban Children with AsthmaR01ES023447 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI MATSUI, ELIZABETH C. · 2014 to 2018
$3.4MMidcareer Investigator Award: Urban School Allergen Exposures and Childhood AsthmK24AI106822 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI PHIPATANAKUL, WANDA · 2013 to 2022
$1.9MATSDR CDC HHS U61 TS000118NCATS NIH HHS UL1 TR001102NHLBI NIH HHS U10 HL098102NIAID NIH HHS K24 AI106822NIAID NIH HHS K24 AI114769NIAID NIH HHS R01 AI073964NIAID NIH HHS U01 AI083238NIAID NIH HHS U01 AI110397NIAID NIH HHS U01 AI126614NICHD NIH HHS K12 HD047349NICHD NIH HHS T32 HD040128NIEHS NIH HHS P30 ES009089NIEHS NIH HHS R01 ES023447
Abstract
PubMed holds no abstract for this paper.
Indexed as
AdolescentAsthmaChildFemaleHumansImmunoglobulin EMalePicornaviridae InfectionsRhinovirusSeverity of Illness IndexImmunoglobulin E
Identifiers
What OpenQuestion holds
Textmetadata
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Read underepoch 390
Registered trials
NCT04670627ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.