ArticleBMC public health2016
Childhood adiposity trajectories are associated with late adolescent blood pressure: birth to twenty cohort.
Article in BMC public health, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
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Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 71 citations in OpenAlex.
- Association of body mass index trajectory and hypertension risk: A systematic review of cohort studies and network meta-analysis of 89,094 participants.Frontiers in cardiovascular medicine · 2022Pooled it
- School-Based Interventions Targeting Nutrition and Physical Activity, and Body Weight Status of African Children: A Systematic Review.Nutrients · 2019Pooled it
- Baseline Targeted Moderation in a Trial of the Family Check-Up 4 Health: Potential Explanations for Finding Few Practical Effects.Prevention science : the official journal of the Society for Prevention Research · 2023Trial
- Childhood BMI trajectories and hypertension in adulthood: a population-based cohort study.Journal of human hypertension · 2026Article
- Article
- Risks and Benefits of Weight Gain in Children With Undernutrition.JAMA network open · 2025Article
- Article
- BMI trajectories from birth to young adulthood associate with distinct cardiometabolic profiles.BMC medicine · 2024Article
- Trajectories of cardiovascular risk predict pregnancy outcomes: The Bogalusa Heart Study and the Cardiovascular Risk in Young Finns Study.Paediatric and perinatal epidemiology · 2024Article
- Association between BMI trajectories from childhood to early adulthood and the carotid intima-media thickness in early adulthood: Tehran lipid and glucose study.BMC public health · 2023Article
- The association of intrauterine and postnatal growth patterns and nutritional status with toddler body composition.BMC pediatrics · 2023Article
- Prevalence and associated factors of hypertension among primary school children: A cross-sectional study in Kuching, Sarawak.Malaysian family physician : the official journal of the Academy of Family Physicians of Malaysia · 2023Article
- Hypertension among adolescents in sub-Saharan Africa: a systematic review.Frontiers in cardiovascular medicine · 2023Review
- Practice Change Needed for the Identification of Pediatric Hypertension in Marginalized Populations: An Example From South Africa.Frontiers in pediatrics · 2022Article
- The effects ofJournal of developmental origins of health and disease · 2021Article
- Trajectories of mid-life to elderly adulthood BMI and incident hypertension: the China Health and Nutrition Survey.BMJ open · 2021Article
- Trajectories of body mass index and risk of incident hypertension among a normal body mass index population: A prospective cohort study.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Stunting in infancy, pubertal trajectories and adult body composition: the Birth to Twenty Plus cohort, South Africa.European journal of clinical nutrition · 2021Article
- Prevalence, incidence, and trends of childhood overweight/obesity in Sub-Saharan Africa: a systematic scoping review.Archives of public health = Archives belges de sante publique · 2020Article
- Body mass index trajectory across childhood and subsequent risk of elevated blood pressure.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundElevated blood pressure in childhood is a risk factor for adult hypertension which is a global health problem. Excess adiposity in childhood creates a predisposition to develop adult hypertension. Our aim was to explore distinct sex-specific adiposity trajectories from childhood to late adolescence and examined their association with blood pressure.
methodsLatent Class Growth Mixture Modeling (LCGMM) on longitudinal data was used to derive sex-specific and distinct body mass index (BMI: kg/m(2)) trajectories. We studied 1824 black children (boys = 877, girls = 947) from the Birth to Twenty (Bt20) cohort from Soweto, South Africa, and obtained BMI measures at ages 5 through 18 years. Participants with at least two age-point BMI measures, were included in the analysis. Analysis of variance (ANOVA), chi-square test, multivariate linear and standard logistic regressions were used to test study characteristics and different associations.
resultsWe identified three (3) and four (4) distinct BMI trajectories in boys and girls, respectively. The overall prevalence of elevated blood pressure (BP) was 34.9 % (39.4 % in boys and 30.38 % in girls). Boys and girls in the early onset obesity or overweight BMI trajectories were more likely to have higher BP values in late adolescence. Compared to those in the normal weight BMI trajectory, girls in early onset obesity trajectories had an increased risk of elevated BP with odds ratio (OR) of 2.18 (95 % confidence interval 1.31 to 4.20) and 1.95 (1.01 to 3.77). We also observed the weak association for boys in early onset overweight trajectory, (p-value = 0.18 and odds ratio of 2.39 (0.67 to 8.57))
conclusionsDistinct weight trajectories are observed in black South African children from as early as 5 years. Early onset adiposity trajectories are associated with elevated BP in both boys and girls. It is important to consider individual patterns of early-life BMI development, so that intervention strategies can be targeted to at-risk individuals.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.