Evidence map›Paper›PMID 27473473›Full record

ArticleBMC pregnancy and childbirth2016

AURORA: bariatric surgery registration in women of reproductive age - a multicenter prospective cohort study.

Goele Jans, Christophe Matthys, Sarah Bel, Lieveke Ameye, Matthias Lannoo, Bart Van der Schueren, Bruno Dillemans, Luc Lemmens, Jean-Pierre Saey, Yves van Nieuwenhove and 8 more

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in BMC pregnancy and childbirth, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02515214 (Bariatric Surgery Registration in Women of Reproductive Age), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02515214 unknown statusnot on this map

Bariatric Surgery Registration in Women of Reproductive Age

Typeobservational_patient_registrySponsorUniversitaire Ziekenhuizen KU LeuvenRan2012 to 2025Enrolled500ConditionsBariatric Surgery Candidate, Pregnancy
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Review: Sex-Specific Aspects in the Bariatric Treatment of Severely Obese Women.International journal of environmental research and public health · 2020
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Obesity in Women: Insights for the Clinician.Journal of women's health (2002) · 2018
    Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Goele JansDepartment of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Belgium. goele.jans@med.kuleuven.be.
Christophe MatthysDepartment of Clinical and Experimental Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Sarah BelScientific Institute of Public Health, Department of Public Health and Surveillance, Unit Surveys, Lifestyle and Chronic Diseases, Juliette Wytsmanstraat 14, 1050, Brussels, Belgium.
Lieveke AmeyeDepartment of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Matthias LannooDepartment of Clinical and Experimental Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Bart Van der SchuerenDepartment of Clinical and Experimental Medicine, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Bruno DillemansDepartment of Abdominal Surgery, St-Jan Hospital Bruges, Ruddershove 10, 8000, Bruges, Belgium.
Luc LemmensDepartment of Abdominal Surgery, St-Nikolaas Hospital, Moerlandstraat 1, 9100, St-Niklaas, Belgium.
Jean-Pierre SaeyMedicosurgical unit for metabolic diseases, CHR Mons Hainaut, 5 avenue Baudouin de Constantinople, 7000, Mons, Belgium.
Yves van NieuwenhoveDepartment of Gastrointestinal Surgery, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Pascale GrandjeanDepartment of Obstetrics and Gynecology, CHR Mons Hainaut, 5 avenue Baudouin de Constantinople, 7000, Mons, Belgium.
Ben De BeckerDepartment of Obstetrics, Gynecology and Reproduction, St-Augustinus Hospital Wilrijk, Oosterveldlaan 24, 2610, Wilrijk, Belgium.
Hilde LoggheDepartment of Obstetrics and Gynecology, St-Lucas Hospital Bruges, St-Lucaslaan 29, 8310, Bruges, Belgium.
Marc CoppensDepartment of Obstetrics and Gynecology, ZNA Middelheim, Lindendreef 1, 2020, Antwerp, Belgium.
Kristien RoelensDepartment of Obstetrics and Gynecology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Anne LoccufierDepartment of Obstetrics and Gynecology, St-Jan Hospital Bruges, Ruddershove 10, 8000, Bruges, Belgium.
Johan VerhaegheDepartment of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
Roland DevliegerDepartment of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
KU Leuven · BEAZ Sint-Jan · BEGhent University Hospital · BEGZA Ziekenhuizen Campus Sint-Augustinus · BEInstitut Scientifique de Santé Publique · BEVlaamse Vereniging voor Obstetrie en Gynaecolo · BEZNA Middelheim Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe expansion of the obesity epidemic is accompanied with an increase in bariatric procedures, in particular in women of reproductive age. The weight loss induced by the surgery is believed to reverse the negative impact of overweight and obesity on female reproduction, however, research is limited to in particular retrospective cohort studies and a growing number of small case-series and case-(control) studies. METHODS/

designAURORA is a multicenter prospective cohort study. The main objective is to collect long-term data on reproductive outcomes before and after bariatric surgery and in a subsequent pregnancy. Women aged 18-45 years are invited to participate at 4 possible inclusion moments: 1) before surgery, 2) after surgery, 3) before 15 weeks of pregnancy and 4) in the immediate postpartum period (day 3-4). Depending on the time of inclusion, data are collected before surgery (T1), 3 weeks and 3, 6, 12 or x months after surgery (T2-T5) and during the first, second and third trimester of pregnancy (T6-T8), at delivery (T9) and 6 weeks and 6 months after delivery (T10-T11). Online questionnaires are send on the different measuring moments. Data are collected on contraception, menstrual cycle, sexuality, intention of becoming pregnant, diet, physical activity, lifestyle, psycho-social characteristics and dietary supplement intake. Fasting blood samples determine levels of vitamin A, D, E, K, B-1, B-12 and folate, albumin, total protein, coagulation parameters, magnesium, calcium, zinc and glucose. Participants are weighted every measuring moment. Fetal ultrasounds and pregnancy course and complications are reported every trimester of pregnancy. Breastfeeding is recorded and breast milk composition in the postpartum period is studied. DISCUSSION: AURORA is a multicenter prospective cohort study extensively monitoring women before undergoing bariatric surgery until a subsequent pregnancy and postpartum period.

trial registrationRetrospectively registered (July 2015 - NCT02515214 ).

Indexed as

Bariatric SurgeryAdolescentAdultBreast FeedingClinical ProtocolsDietDietary SupplementsFemaleHumansLife StyleMenstrual CycleMiddle AgedMilk, HumanObesityPostoperative PeriodPregnancyBariatric surgeryBreast feedingContraceptionFertilityObesityPregnancyReproduction

Identifiers

PMID27473473
PMCPMC4966861
OpenAlexW2504781363

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.