Evidence map›Paper›PMID 27473316›Full record

ArticleG3 (Bethesda, Md.)2016

Characterization of a Novel MMS-Sensitive Allele of Schizosaccharomyces pombe mcm4.

Nimna S Ranatunga, Susan L Forsburg

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. MonitoringBiology open · 2021
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nimna S RanatungaProgram in Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089.
Susan L ForsburgProgram in Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089 forsburg@usc.edu.ORCID 0000-0002-4895-8598
University of Southern California · US

Funding

Mechanisms linking replication stress to genome instability in fission yeastR35GM118109 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2016 to 2025
$7.1M
Checkpoints and Double Strand Breaks in S. Pombe MeiosisR01GM081418 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2009 to 2014
$2.2M
Structural instability and DNA rearrangements in the centromereR01GM111040 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FORSBURG, SUSAN L · 2014 to 2015
$626k
NIGMS NIH HHS R01 GM081418NIGMS NIH HHS R01 GM111040NIGMS NIH HHS R35 GM118109
6 · The paper itself

Abstract

The minichromosome maintenance (MCM) complex is the conserved helicase motor of the eukaryotic replication fork. Mutations in the Mcm4 subunit are associated with replication stress and double strand breaks in multiple systems. In this work, we characterize a new temperature-sensitive allele of Schizosaccharomyces pombe mcm4

Indexed as

AllelesAntineoplastic Agents, AlkylatingChromosome SegregationDNA DamageDNA RepairDNA ReplicationMethyl MethanesulfonateMicrobial ViabilityMinichromosome Maintenance Complex Component 4MutationPhenotypeSchizosaccharomycesSchizosaccharomyces pombe ProteinsAntineoplastic Agents, AlkylatingMethyl MethanesulfonateMinichromosome Maintenance Complex Component 4Schizosaccharomyces pombe ProteinscheckpointDNA replicationfission yeastfork protection complexMCM complexMMS

Identifiers

PMID27473316
PMCPMC5068930
OpenAlexW2499284689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.