Evidence map›Paper›PMID 27473164›Full record

Trial reportArthritis research & therapy2016

Resistance exercise improves physical fatigue in women with fibromyalgia: a randomized controlled trial.

Anna Ericsson, Annie Palstam, Anette Larsson, Monika Löfgren, Indre Bileviciute-Ljungar, Jan Bjersing, Björn Gerdle, Eva Kosek, Kaisa Mannerkorpi

3 registry-linked trialsOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Arthritis research & therapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 36 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 12 pooled it
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01226784 nacompletednot on this map

The Effects of Training and Relaxation on Fibromyalgia.

TypeinterventionalSponsorKarolinska InstitutetRan2010 to 2020Enrolled240ConditionsFibromyalgiaArmsPhyscial activity
NCT02859467 nasuspendednot on this map

Benefits of Kinesio Taping and Inhibitory Treatment Techniques in Patients With Fibromyalgia Syndrome

TypeinterventionalSponsorUniversidad de AlmeriaRan2016 to 2024Enrolled64ConditionsFibromyalgiaArmsKinesio Taping and Inhibitory Treatment Techniques, Exercise and Electrical Stimulation Therapy
NCT02864524 naunknown statusnot on this map

Effects of Manipulative Therapy in the Lower Thoracic and Cervical Spine in Subjects With Fibromyalgia Syndrome

TypeinterventionalSponsorUniversidad de AlmeriaRan2016 to 2021Enrolled64ConditionsFibromyalgiaArmsManipulative and Massage Therapy, Exercise Program
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 12 syntheses or guidelines pooled it, 91 citations in OpenAlex.

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  18. [Effects of exercise interventions on anxiety and depressive symptoms in patients with fibromyalgia syndrome: a meta-analysis].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anna EricssonInstitute of Neuroscience and Physiology/Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden. anna.ericsson@vgregion.se.
Annie PalstamInstitute of Neuroscience and Physiology/Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
Anette LarssonInstitute of Neuroscience and Physiology/Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
Monika LöfgrenKarolinska Institutet, Department of Clinical Sciences, Danderyd Hospital Stockholm, Stockholm, Sweden.
Indre Bileviciute-LjungarKarolinska Institutet, Department of Clinical Sciences, Danderyd Hospital Stockholm, Stockholm, Sweden.
Jan BjersingInstitute of Medicine, Department of Rheumatology and Inflammation research, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
Björn GerdleDepartment of Medical and Health Sciences, Division of Community Medicine, Faculty of Medicine and Health Sciences, Linköping University, Pain and Rehabilitation Center, Anesthetics, Operations and Specialty Surgery Center, Region Östergötland, Linköping, Sweden.
Eva KosekDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Kaisa MannerkorpiInstitute of Neuroscience and Physiology/Physiotherapy, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden.
University of Gothenburg · SEKarolinska Institutet · SELinköping University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFibromyalgia (FM) affects approximately 1-3 % of the general population. Fatigue limits the work ability and social life of patients with FM. A few studies of physical exercise have included measures of fatigue in FM, indicating that exercise can decrease fatigue levels. There is limited knowledge about the effects of resistance exercise on multiple dimensions of fatigue in FM. The present study is a sub-study of a multicenter randomized controlled trial in women with FM. The purpose of the present sub-study was to examine the effects of a person-centered progressive resistance exercise program on multiple dimensions of fatigue in women with FM, and to investigate predictors of the potential change in fatigue.

methodsA total of 130 women with FM (age 22-64 years) were included in this assessor-blinded randomized controlled multicenter trial examining the effects of person-centered progressive resistance exercise compared with an active control group. The intervention was performed twice a week for 15 weeks. Outcomes were five dimensions of fatigue measured with the Multidimensional Fatigue Inventory (MFI-20). Information about background was collected and the women also completed several health-related questionnaires. Multiple linear stepwise regression was used to analyze predictors of change in fatigue in the total population.

resultsA higher improvement was found at the post-treatment examination for change in the resistance exercise group, as compared to change in the active control group in the MFI-20 subscale of physical fatigue (resistance group Δ -1.7, SD 4.3, controls Δ 0.0, SD 2.7, p = 0.013), with an effect size of 0.33. Sleep efficiency was the strongest predictor of change in the MFI-20 subscale general fatigue (beta = -0.54, p = 0.031, R (2) = 0.05). Participating in resistance exercise (beta = 1.90, p = 0.010) and working fewer hours per week (beta = 0.84, p = 0.005) were independent significant predictors of change in physical fatigue (R (2) = 0.14).

conclusionsPerson-centered progressive resistance exercise improved physical fatigue in women with FM when compared to an active control group.

trial registrationClinicalTrials.gov NCT01226784 . Registered 21 October 2010.

Indexed as

AdultFatigueFemaleFibromyalgiaHumansMiddle AgedResistance TrainingSurveys and QuestionnairesSwedenYoung AdultExerciseFatigueFibromyalgiaRandomized controlled trialResistance exercise

Identifiers

PMID27473164
PMCPMC4967304
OpenAlexW2500676669

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.