Evidence map›Paper›PMID 27472992›Full record

ReviewQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2016

EQ-5D in Central and Eastern Europe: 2000-2015.

Fanni Rencz, László Gulácsi, Michael Drummond, Dominik Golicki, Valentina Prevolnik Rupel, Judit Simon, Elly A Stolk, Valentin Brodszky, Petra Baji, Jakub Závada and 3 more

Registry-linked trialAbstract readHistorical ArticleReview
PubMed Publisher
In one paragraph

Review in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04647097 (Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking), which is not on this map. Cited by 98 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04647097 narecruitingnot on this mapstarted 2022, after this paper: background citation

Recurrent Acute Pancreatitis Prevention by the Elimination of Alcohol and Cigarette Smoking (REAPPEAR): Protocol of a Randomized Controlled Trial and a Cohort Study

TypeinterventionalSponsorUniversity of PecsRan2022 to 2028Enrolled364ConditionsAcute Pancreatitis, Recurrent Acute PancreatitisArmsStandard intervention only, Standard intervention plus repeated intervention
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Psychometric properties of the EQ-5D-5L: a systematic review of the literature.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
    Pooled it
  4. EQ-5D studies in nervous system diseases in eight Central and East European countries: a systematic literature review.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Pooled it
  5. Cost-of-illness studies in nine Central and Eastern European countries.The European journal of health economics : HEPAC : health economics in prevention and care · 2019
    Pooled it
  6. Pooled it
  7. Article
  8. Article
  9. A direct comparison of the measurement properties of the PROMIS-16 and EQ-5D-5L in the U.S. general population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  10. Comparing the measurement properties of the EQ-5D-Y-3L and EQ-5D-3L in a general population sample of adults.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  11. Article
  12. Qualitative testing of the EQ-HWB-9 with a 'blank' EQ-HWB VAS and EQ-5D-5L with skin bolt-ons in a rare genetic skin disease population.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  13. Testing culturally relevant EQ-5D-5L bolt-ons for the Chinese general population: first quantitative phase of a mixed methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  14. Article
  15. Article
  16. The psychometric performance of the EQ-5D-5L composite and component items in the U.S. General population and by age group.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  17. Article
  18. Identifying and developing culturally relevant EQ-5D-5L bolt-on items for Chinese population: qualitative phase of a mixed-methods study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  19. Psychometric benefits of adding bolt-ons to the EQ-5D-5L in populations undergoing minimally invasive cosmetic procedures.The European journal of health economics : HEPAC : health economics in prevention and care · 2025
    Article
  20. Valuing health-related quality of life: an EQ-5D-5L value set for Morocco.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fanni RenczDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8., Budapest, H-1093, Hungary.
László GulácsiDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8., Budapest, H-1093, Hungary. laszlo.gulacsi@uni-corvinus.hu.
Michael DrummondCentre for Health Economics, University of York, Heslington, York, YO10 5DD, UK.
Dominik GolickiDepartment of Experimental and Clinical Pharmacology, Medical University of Warsaw, Poland, ul. Banacha 1b, 02-097, Warsaw, Poland.
Valentina Prevolnik RupelInstitute for Economic Research, Kardeljeva ploščad 17, 1000, Ljubljana, Slovenia.
Judit SimonDepartment of Health Economics, Centre for Public Health, Medical University of Vienna, Kinderspitalgasse 15/1, 1090, Vienna, Austria.
Elly A StolkInstitute of Health Policy and Management, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands.
Valentin BrodszkyDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8., Budapest, H-1093, Hungary.
Petra BajiDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8., Budapest, H-1093, Hungary.
Jakub ZávadaInstitute of Rheumatology, 1st Faculty of Medicine, Charles University, Na Slupi 4, 128 00, Prague, Czech Republic.
Guenka PetrovaDepartment of Social Pharmacy and Pharmacoeconomics, Faculty of Pharmacy, Medical University, Sofia, Bulgaria.
Alexandru RotarDepartment of Social Medicine, University of Amsterdam, Meibergdreef 9, 22660, 1100 DD, Amsterdam, The Netherlands.
Márta PéntekDepartment of Health Economics, Corvinus University of Budapest, Fővám tér 8., Budapest, H-1093, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCost per quality-adjusted life year data are required for reimbursement decisions in many Central and Eastern European (CEE) countries. EQ-5D is by far the most commonly used instrument to generate utility values in CEE. This study aims to systematically review the literature on EQ-5D from eight CEE countries.

methodsAn electronic database search was performed up to 1 July 2015 to identify original EQ-5D studies from the countries of interest. We analysed the use of EQ-5D with respect to clinical areas, methodological rigor, population norms and value sets.

resultsWe identified 143 studies providing 152 country-specific results with a total sample size of 81,619: Austria (n = 11), Bulgaria (n = 6), Czech Republic (n = 18), Hungary (n = 47), Poland (n = 51), Romania (n = 2), Slovakia (n = 3) and Slovenia (n = 14). Cardiovascular (21 %), neurologic (17 %), musculoskeletal (15 %) and endocrine, nutritional and metabolic diseases (13 %) were the most frequently studied clinical areas. Overall, 112 (78 %) of the studies reported EQ VAS results and 86 (60 %) EQ-5D index scores, of which 27 (31 %) did not specify the applied tariff. Hungary, Poland and Slovenia have population norms. Poland and Slovenia also have a national value set.

conclusionsIncreasing use of EQ-5D is observed throughout CEE. The spread of health technology assessment activities in countries seems to be reflected in the number of EQ-5D studies. However, improvement in informed use and methodological quality of reporting is needed. In jurisdictions where no national value set is available, in order to ensure comparability we recommend to apply the most frequently used UK tariff. Regional collaboration between CEE countries should be strengthened.

Indexed as

Cost-Benefit AnalysisEuropeHistory, 21st CenturyHumansMaleQuality-Adjusted Life YearsQuality of LifeSurveys and QuestionnairesCentral and Eastern EuropeCost-effectiveness analysisEQ-5DHealth-related quality of lifeHealth technology assessmentValue sets

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.