Evidence map›Paper›PMID 27472986›Full record

ArticleDevelopmental psychobiology2017

Infant hair cortisol: associations with salivary cortisol and environmental context.

Megan Flom, Ashley M St John, Jerrold S Meyer, Amanda R Tarullo

Registry-linked trialAbstract read
In one paragraph

Article in Developmental psychobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04107506 (RCT of FIND Video Coaching Intervention for Caregivers Facing Economic Adversity), which is not on this map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04107506 nacompletednot on this mapstarted 2019, after this paper: background citation

RCT of FIND Video Coaching Intervention for Caregivers Facing Economic Adversity

TypeinterventionalSponsorUniversity of OregonRan2019 to 2025Enrolled160ConditionsChild Behavior, Parent-Child RelationsArmsFilming Interactions to Nurture Development, The Healthy Toddler Program
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Hair collection protocol in 12-month-old infants.Comprehensive psychoneuroendocrinology · 2024
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  7. Review
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  15. Social Fear in US Infants: The Roles of Hair and Salivary Cortisol.The Yale journal of biology and medicine · 2022
    Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Megan FlomDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.
Ashley M St JohnDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.
Jerrold S MeyerDepartment of Psychological & Brain Sciences, University of Massachusetts, Amherst, Massachusetts.
Amanda R TarulloDepartment of Psychological and Brain Sciences, Boston University, Boston, Massachusetts.
Boston University · USUniversity of Massachusetts Amherst · US

Funding

Hair Cortisol as a Biomarker of Chronic Early Life StressR03HD082550 · NICHD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI TARULLO, AMANDA · 2015 to 2016
$177k
NICHD NIH HHS R03 HD082550
6 · The paper itself

Abstract

Early chronic stress has enduring implications for physical and mental health outcomes. Hair cortisol concentration (HCC) has emerged as a marker of cumulative cortisol exposure, yet HCC in infants is not well understood. We examined how infant HCC relates to widely used basal salivary cortisol measures, maternal HCC, and environmental context in 111 infants assessed at 6 and 12 months of age. Maternal HCC at 6 and 12 months was correlated with infant HCC at 12 months. At 12 months, infant HCC was positively associated with waking salivary cortisol concentration (SCC), evening SCC, and area under the curve (AUC), but was independent of diurnal slope. Breastfeeding was associated with lower HCC, whereas increased sleep disruption was related to flatter slope. Reduced nighttime sleep duration was related both to higher HCC and to flatter slope. A person-focused analysis indicated that the combination of high HCC and flattened slope was associated with more environmental risks, highlighting the importance of investigating the interplay between HCC and diurnal cortisol slope. Results support the validity of HCC as a marker of cumulative cortisol exposure in infancy, while emphasizing the value of including multiple cortisol measures assessing distinct aspects of hypothalamic-pituitary-adrenal (HPA) function.

Indexed as

EnvironmentMother-Child RelationsAdultBreast FeedingDepressionFemaleHairHumansHydrocortisoneInfantMothersParentingSalivaSleepStress, PsychologicalHydrocortisonebreastfeedingdiurnal cortisolhair cortisolinfancysleepsocioeconomic status

Identifiers

PMID27472986
PMCPMC6203946
OpenAlexW2511528359

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.