Evidence map›Paper›PMID 27472943›Full record

ArticleHealth economics review2016

What, who and when? Incorporating a discrete choice experiment into an economic evaluation.

Michela Tinelli, Mandy Ryan, Christine Bond

Open access · goldAbstract read
In one paragraph

Article in Health economics review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
11.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. A Pilot Economic Evaluation of a Nature-Based Therapy for Chronic Obstructive Pulmonary Disease in Austria.International journal of environmental research and public health · 2026
    Trial
  2. Do preferences differ based on respondent experience of a health issue and its treatment? A case study using a public health intervention.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Trial
  3. Trial
  4. Article
  5. Is next generation sequencing for the diagnosis of rare diseases worth its cost? A user-based approach to valuation.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  6. Article
  7. Article
  8. Treatment Preferences for Acute Allergic Reactions: A Discrete Choice Experiment.Journal of health economics and outcomes research · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Consumer Reactions toFrontiers in veterinary science · 2020
    Article
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  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Michela TinelliLSE Health and Social Care, the London School of Economics and Political Science, Houghton Street, London, WC2A 2AE, UK. m.tinelli@lse.ac.uk.
Mandy RyanHealth Economics Research Unit, University of Aberdeen, Polwarth Building, Foresterhill campus, AB25 2ZD, Aberdeen, Scotland.
Christine BondCentre of Academic Primary Care, University of Aberdeen, Polwarth Building, Foresterhill campus, AB25 2ZD, Aberdeen, Scotland.
University of Aberdeen · GBLondon School of Economics and Political Science · GB

Funding

Chief Scientist Office HERU1
6 · The paper itself

Abstract

backgroundEconomic evaluation focuses on Quality-Adjusted-Life-Years (QALYs) as the main valuation method. However, it is well known that factors beyond health related quality of life are important to patients and the public. Whilst discrete-choice-experiments (DCE) have been extensively used to value such factors, their incorporation within an economic evaluation framework is limited. This study is the first to incorporate patient preferences for factors beyond QALYs into an economic evaluation and compare results with the standard cost-per-QALY approach, using randomised-controlled-trial (RCT) participants.

methodsCostings, clinical-effectiveness (appropriateness-of-treatment), QALYs and patient satisfaction data were collected at baseline and 12-month follow-up for a new pharmacy-service within a randomised-controlled-trial. Trial participants who replied to the follow-up survey and had not subsequently withdrawn from the study were mailed a DCE questionnaire at 24-months. WTP for the standard and new service was derived from the DCE. Results from QALYs and the DCE were compared.

resultsAt 12 months, costs, clinical-effectiveness and QALYs did not differ between the intervention and control; however there was a significant increase in satisfaction in the intervention. The DCE valued this increased satisfaction in the intervention (positive net-benefit). The longer the time patients experienced the new service the greater the reported net-benefit.

conclusionWhen incorporating a DCE into an economic evaluation a number of questions are raised: what factors should be valued, whose values (trial-groups vs. all-trial-population) and when should they be elicited (still-receiving-the-intervention or afterwards). Consideration should also be given to status quo bias.

Indexed as

Cost-benefit analysis (CBA)Discrete choice experiment (DCE)Economic evaluationQuality adjusted life year (QALY)Randomised controlled trial (RCT)Willingness to pay (WTP)

Identifiers

PMID27472943
PMCPMC4967060
OpenAlexW2504599303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.