Evidence map›Paper›PMID 27472724›Full record

SynthesisMedicine2016

The prevalence of tic disorders for children in China: A systematic review and meta-analysis.

Chunsong Yang, Lingli Zhang, Ping Zhu, Cairong Zhu, Qin Guo

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06924918 (Scalp Acupuncture Treatment for Chronic Tic Disorders in Children), which is not on this map. Cited by 57 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 14 pooled it
6.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06924918 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

Scalp Acupuncture Treatment for Chronic Tic Disorders in Children: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorChildren's Hospital of Fudan UniversityRan2025 to 2027Enrolled136ConditionsTic DisorderArmsScalp Acupuncture Treatment, Tuina Treatment Group
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 14 syntheses or guidelines pooled it, 106 citations in OpenAlex.

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  16. Tourette syndrome.Nature reviews. Disease primers · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Chunsong YangDepartment of Pharmacy, Evidence-Based Pharmacy Center, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children West China School of Public Health Department of Pediatrics, West China Second Hospital, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Chengdu, Sichuan Province, China.
Lingli Zhang
Ping Zhu
Cairong Zhu
Qin Guo
Chengdu Medical College · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTic disorders (TD) are common neuropsychiatric disorders among children and adolescents. Still, there is great uncertainty regarding their epidemiology in China. We aim to depict the prevalence of TD for children in China and explore the influence of sex, age, geographic distribution, and diagnostic criteria on the prevalence rates.

methodsWe searched PubMed, EMBASE, four Chinese electronic databases, and relevant lists. Two reviewers independently selected trials, assessed trial quality, and extracted the data.

resultsWe included 13 studies investigating 269,571 participants. The sample size ranged from 563 to 216,005 participants. The age of participants ranged from 3 to 16 years. The meta-analysis of the prevalence of TD was 6.1% [95% CI: 0.036-0.100, I = 49.7%]. The prevalence of transient tic disorder (TTD), chronic tic disorder (CTD), and Tourette syndrome (TS) was 1.7% [95% CI = 0.009-0.031, I = 49%], 1.2% [95% CI = 0.007-0.022, I = 48.3%], and 0.3% [95% CI = 0.001-0.008, I = 49.5%], respectively. The prevalence of TD in boys [5.1%, 95% CI = 0.026-0.098, I = 49.3%] was higher than that in girls [2.4%, 95% CI = 0.009-0.065, I = 49.4%]. The prevalence of TD in urban area [2.6%, 95% CI = 0.019-0.034, I = 35.5%] was higher than that in rural area [2.2%, 95% CI = 0.016-0.030, I = 33.9%]. The prevalence of TD in central China [10.7%, 95% CI = 0.043-0.242, I = 49.2%] was higher than that in North China [7.8%, 95% CI = 0.007-0.522, I = 49.9%] and East China [4.4%, 95% CI = 0.015-0.120, I = 49.8%].

conclusionTD is a common disease in China, with prevalence differing based on sex, age, and region.

Indexed as

AdolescentAge FactorsChildChild, PreschoolChinaCross-Sectional StudiesFemaleHumansMaleSex FactorsTic Disorders

Identifiers

PMID27472724
PMCPMC5265861
OpenAlexW2478521556

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.