Evidence map›Paper›PMID 27472428›Full record

ReviewSeminars in thrombosis and hemostasis2017

α2-Antiplasmin: New Insights and Opportunities for Ischemic Stroke.

Guy L Reed, Aiilyan K Houng, Satish Singh, Dong Wang

Abstract readReview
In one paragraph

Review in Seminars in thrombosis and hemostasis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Guideline
  2. The Role of Biomarkers in Atherothrombotic Stroke-A Systematic Review.International journal of molecular sciences · 2021
    Pooled it
  3. Pooled it
  4. Review
  5. Thromboinflammation in dogs with virulent babesiosis.Frontiers in veterinary science · 2026
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Immune cell-mediated venous thrombus resolution.Research and practice in thrombosis and haemostasis · 2023
    Review
  11. Plasminogen System in the Pathophysiology of Sepsis: Upcoming Biomarkers.International journal of molecular sciences · 2023
    Review
  12. Review
  13. Article
  14. Fibrinogen and Factor XIII in Venous Thrombosis and Thrombus Stability.Arteriosclerosis, thrombosis, and vascular biology · 2022
    Review
  15. Uncovering the Neuroprotective Effect ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Assessing Plasmin Generation in Health and Disease.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Guy L ReedDepartment of Medicine, University of Tennessee Health Sciences Center, Memphis, Tennessee.
Aiilyan K HoungDepartment of Medicine, University of Tennessee Health Sciences Center, Memphis, Tennessee.
Satish SinghDepartment of Medicine, University of Tennessee Health Sciences Center, Memphis, Tennessee.
Dong WangDepartment of Medicine, University of Tennessee Health Sciences Center, Memphis, Tennessee.
University of Tennessee Health Science Center · US

Funding

Alpha-2-antiplasmin and Ischemic StrokeR01NS089707 · NINDS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI REED, GUY L · 2015 to 2019
$1.9M
NINDS NIH HHS R01 NS089707
6 · The paper itself

Abstract

Thrombotic vascular occlusion is the leading cause of ischemic stroke. High blood levels of α

Indexed as

alpha-2-AntiplasminHumansStrokealpha-2-Antiplasmin

Identifiers

PMID27472428
PMCPMC5592111
OpenAlexW2494356700

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.