ArticleFrontiers in neuroscience2016
Neural Biomarkers for Dyslexia, ADHD, and ADD in the Auditory Cortex of Children.
Article in Frontiers in neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.
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Who cites it
53 citing papers in PubMed, 5 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- Outcomes of music therapy on children and adolescents with attention-deficit/hyperactivity disorder: a systematic review and meta-analysis.Trends in psychiatry and psychotherapy · 2025Pooled it
- Effects of Music on Attention-Deficit/Hyperactivity Disorder (ADHD) and Potential Application in Serious Video Games: Systematic Review.Journal of medical Internet research · 2023Pooled it
- Evaluation of Risk of Bias in Neuroimaging-Based Artificial Intelligence Models for Psychiatric Diagnosis: A Systematic Review.JAMA network open · 2023Pooled it
- Musical development during adolescence: Perceptual skills, cognitive resources, and musical training.Annals of the New York Academy of Sciences · 2022Pooled it
- The use of noninvasive brain stimulation techniques to improve reading difficulties in dyslexia: A systematic review.Human brain mapping · 2022Pooled it
- Effects of music therapy as an alternative treatment on depression in children and adolescents with ADHD by activating serotonin and improving stress coping ability.BMC complementary medicine and therapies · 2023Trial
- Intergenerational transmission of the structure of the auditory cortex and reading skills.Developmental cognitive neuroscience · 2026Article
- Rediscovery of a seventh sense: humans produce, perceive, and process ultrasound.Frontiers in neuroscience · 2026Article
- Neurophysiological and biological effects of music-based interventions in ADHD: a mini review.Frontiers in psychiatry · 2026Review
- Phenome-wide analysis of genetically imputed neuroimaging phenotypes reveals associations with psychiatric traits in a multi-ancestry cohort.medRxiv : the preprint server for health sciences · 2025Article
- Altered auditory attention and functional connectivity in the auditory cortex of children with Attention-Deficit/Hyperactivity Disorder.BMC psychiatry · 2025Article
- Epidemiological Investigation on the Clinical Status of the Developmental Dyslexia and ADHD Comorbidity among School-Age Children in Pakistan.Open journal of epidemiology · 2025Article
- Article
- Language aptitude is related to the anatomy of the transverse temporal gyri.Brain structure & function · 2024Article
- Self-Perceived Stress and the Personality of Mothers of Children with Central Auditory Processing Disorder, as Well as in Mothers of Typically Developing Children, Before and Late in the COVID-19 Pandemic.Audiology research · 2024Article
- Paediatric magnetoencephalography and its role in neurodevelopmental disorders.The British journal of radiology · 2024Review
- Genetic Variants Linked to Dyslexia Co-Morbid ADHD: A Case Study of a Pakistani Outpatient.Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique · 2024Article
- Misjudgement of One's Own Performance? Exploring Attention Deficit (Hyperactivity) Disorder (ADHD) and Individual Difference in Complex Music and Foreign Language Perception.International journal of environmental research and public health · 2023Article
- Neuroanatomical Disposition, Natural Development, and Training-Induced Plasticity of the Human Auditory System from Childhood to Adulthood: A 12-Year Study in Musicians and Nonmusicians.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Sampling inequalities affect generalization of neuroimaging-based diagnostic classifiers in psychiatry.BMC medicine · 2023Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dyslexia, attention deficit hyperactivity disorder (ADHD), and attention deficit disorder (ADD) show distinct clinical profiles that may include auditory and language-related impairments. Currently, an objective brain-based diagnosis of these developmental disorders is still unavailable. We investigated the neuro-auditory systems of dyslexic, ADHD, ADD, and age-matched control children (N = 147) using neuroimaging, magnetencephalography and psychoacoustics. All disorder subgroups exhibited an oversized left planum temporale and an abnormal interhemispheric asynchrony (10-40 ms) of the primary auditory evoked P1-response. Considering right auditory cortex morphology, bilateral P1 source waveform shapes, and auditory performance, the three disorder subgroups could be reliably differentiated with outstanding accuracies of 89-98%. We therefore for the first time provide differential biomarkers for a brain-based diagnosis of dyslexia, ADHD, and ADD. The method allowed not only allowed for clear discrimination between two subtypes of attentional disorders (ADHD and ADD), a topic controversially discussed for decades in the scientific community, but also revealed the potential for objectively identifying comorbid cases. Noteworthy, in children playing a musical instrument, after three and a half years of training the observed interhemispheric asynchronies were reduced by about 2/3, thus suggesting a strong beneficial influence of music experience on brain development. These findings might have far-reaching implications for both research and practice and enable a profound understanding of the brain-related etiology, diagnosis, and musically based therapy of common auditory-related developmental disorders and learning disabilities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.