ArticleTherapeutics and clinical risk management2016
Is there a relationship between fracture healing and mean platelet volume?
Article in Therapeutics and clinical risk management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Posterior Olecranon Fracture Dislocations in Adults: A Systematic Review.Orthopaedic surgery · 2023Pooled it
- Reliable assessment of bone marrow and bone marrow concentrates using automated hematology analyzer.Regenerative medicine · 2019Trial
- Immune-cancer analyses across mammals reveal a potential trophic level and platelet-linked tradeoff between cancer and trauma mortality.bioRxiv : the preprint server for biology · 2025Article
- Complete Blood Count Parameters and Bone Health: Clinical and Experimental Evidence.Endocrinology and metabolism (Seoul, Korea) · 2025Review
- Poor radiological outcomes and associated factors among tibial shaft fracture patients treated with intramedullary nail fixation at Addis Ababa Burn, Emergency and Trauma Hospital, Ethiopia.Frontiers in surgery · 2025Article
- Displaced Femoral Neck Fractures Treated with Percutaneous Compression Plates in Elderly Individuals: An Effect Analysis Based on Imaging.Current medical imaging · 2025Article
- Calcaneal distraction vs. cast immobilization for the preoperative treatment of patients with Danis-Weber type C ankle fractures: a case-control study.Frontiers in surgery · 2024Article
- Management of comminuted patellar fractures using suture reduction technique combined with the modified Kirschner-wire tension band.BMC surgery · 2023Article
- Effect of Tricalcium Phosphate on Healing of Non-Unions: An Observational Study of over 400 Non-Unions.Therapeutics and clinical risk management · 2023Article
- The Surgical Timing and Complications of Rib Fixation for Rib Fractures in Geriatric Patients.Journal of personalized medicine · 2022Article
- Ethical Dilemmas with Regard to Elderly Patients with Hip Fracture: The Problem of Nonagenarians and Centenarians.Journal of clinical medicine · 2022Article
- Effect of calcium and magnesium on inflammatory cytokines in accidentally multiple fracture adults: A short-term follow-up.Medicine · 2022Article
- Contralateral non-simultaneous proximal femoral fractures in patients over 65 years old.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- Global Research Status and Trends of Femoral Neck Fracture Over the Past 27 Years: A Historical Review and Bibliometric Analysis.Frontiers in surgery · 2022Article
- Use of three-dimensional-printed custom-made prosthesis to treat unicondylar femoral defect secondary to pathological fracture caused by giant cell tumor.The Journal of international medical research · 2021Article
- An analysis of perioperative hidden blood loss in femoral intertrochanteric fractures: bone density is an important influencing factor.BMC musculoskeletal disorders · 2021Article
- Treatment of anterior column posterior hemitransverse fracture with supra-ilioinguinal approach.The Journal of international medical research · 2021Article
- Additional table for easier access to ankle fracture: A retrospective study of traditional positioning versus modified positioning.Medicine · 2020Article
- Concurrent ipsilateral Tillaux fracture and medial malleolar fracture in adolescents: management and outcome.Journal of orthopaedic surgery and research · 2020Article
- Preincubation with a low-dose hydrogen peroxide enhances anti-oxidative stress ability of BMSCs.Journal of orthopaedic surgery and research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPlatelet volume has been defined to be a marker that shows thrombocyte activation and function and it is measured as mean platelet volume (MPV). MPV shows the mean volume of circulating thrombocytes and it is one of the routine parameters in complete blood count. Increased thrombocyte volume is associated with thrombocyte activation. PATIENTS AND
methodsThis study included 76 patients who were operated on due to fractures of long tubular bones. Patients who had union without any additional interventions were defined as group I, and patients who needed additional interventions due to nonunion or inadequate union were defined as group II. The control group included healthy volunteers who did not have a fracture. Hematologic test values of the patients that were obtained at admission to emergency ward were recorded.
resultsThe groups were not statistically different in terms of age, sex, and the affected extremity. There were significant differences between group I and group II in terms of mean erythrocyte sedimentation rate, C-reactive protein, and MPV values (P<0.001), but there were no significant differences between group I and the control group. There was also no statistically significant difference among groups in terms of hematologic and biochemical variables.
conclusionIn our study, fractures in patients who had lower MPV values than controls during the inflammation process healed without any problem, but fractures in patients with high MPV values more frequently needed additional surgical interventions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.