ArticleBiosensors & bioelectronics2017
Detecting explosive molecules from nanoliter solution: A new paradigm of SERS sensing on hydrophilic photonic crystal biosilica.
Article in Biosensors & bioelectronics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- SERS-Based Local Field Enhancement in Biosensing Applications.Molecules (Basel, Switzerland) · 2024Review
- Plasmonic nanoparticle sensors: current progress, challenges, and future prospects.Nanoscale horizons · 2024Review
- Nanoplasmonic biosensors for environmental sustainability and human health.Chemical Society reviews · 2024Review
- Selective SERS Detection of TATB Explosives Based on Hydroxy-Terminal Nanodiamond-Multilayer Graphene Substrate.ACS omega · 2024Article
- Limit-Defying μ-Total Analysis System: Achieving Part-Per-Quadrillion Sensitivity on a Hierarchical Optofluidic SERS Sensor.ACS omega · 2023Article
- Diatom biosilica in plasmonics: applications in sensing, diagnostics and therapeutics [Invited].Biomedical optics express · 2022Review
- Diatom Frustule Array for Flow-Through Enhancement of Fluorescent Signal in a Microfluidic Chip.Micromachines · 2021Article
- Hybrid Nanoplasmonic Porous Biomaterial Scaffold for Liquid Biopsy Diagnostics Using Extracellular Vesicles.ACS sensors · 2020Article
- Design and simulation of diatom-based microcantilever immunobiosensor for the early detection of Karnal bunt.3 Biotech · 2020Article
- Interpol review of detection and characterization of explosives and explosives residues 2016-2019.Forensic science international. Synergy · 2020Review
- Recent Advances on Diatom-Based Biosensors.Sensors (Basel, Switzerland) · 2019Review
- Quantitative TLC-SERS detection of histamine in seafood with support vector machine analysis.Food control · 2019Article
- Biological Photonic Crystal-Enhanced Plasmonic Mesocapsules: Approaching Single-Molecule Optofluidic-SERS Sensing.Advanced optical materials · 2019Article
- Photonic Crystal-Enhanced Fluorescence Imaging Immunoassay for Cardiovascular Disease Biomarker Screening with Machine Learning Analysis.Sensors and actuators. B, Chemical · 2019Article
- Microfluidic Diatomite Analytical Devices for Illicit Drug Sensing with ppb-Level Sensitivity.Sensors and actuators. B, Chemical · 2018Article
- Diatomite Photonic Crystals for Facile On-Chip Chromatography and Sensing of Harmful Ingredients from Food.Materials (Basel, Switzerland) · 2018Article
- Ultrasensitive SERS immunoassay based on diatom biosilica for detection of interleukins in blood plasma.Analytical and bioanalytical chemistry · 2017Article
- Plasmonic nanoparticles-decorated diatomite biosilica: extending the horizon of on-chip chromatography and label-free biosensing.Journal of biophotonics · 2017Article
- Chemical and Biological Sensing Using Diatom Photonic Crystal Biosilica With In-Situ Growth Plasmonic Nanoparticles.IEEE transactions on nanobioscience · 2016Article
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Authors and funding
8 authors.
Funding
Abstract
We demonstrate a photonic crystal biosilica surface-enhanced Raman scattering (SERS) substrate based on a diatom frustule with in-situ synthesized silver nanoparticles (Ag NPs) to detect explosive molecules from nanoliter (nL) solution. By integrating high density Ag NPs inside the nanopores of diatom biosilica, which is not achievable by traditional self-assembly techniques, we obtained ultra-high SERS sensitivity due to dual enhancement mechanisms. First, the hybrid plasmonic-photonic crystal biosilica with three dimensional morphologies was obtained by electroless-deposited Ag seeds at nanometer sized diatom frustule surface, which provides high density hot spots as well as strongly coupled optical resonances with the photonic crystal structure of diatom frustules. Second, we discovered that the evaporation-driven microscopic flow combined with the strong hydrophilic surface of diatom frustules is capable of concentrating the analyte molecules, which offers a simple yet effective mechanism to accelerate the mass transport into the SERS substrate. Using the inkjet printing technology, we are able to deliver multiple 100pico-liter (pL) volume droplets with pinpoint accuracy into a single diatom frustule with dimension around 30µm×7µm×5µm, which allows for label-free detection of explosive molecules such as trinitrotoluene (TNT) down to 10
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