SynthesisScientific reports2016
Acupuncture for musculoskeletal pain: A meta-analysis and meta-regression of sham-controlled randomized clinical trials.
Synthesis in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04464954 (Pilot Study), which is not on this map. Cited by 86 papers, 16 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study: Effect of Battlefield Acupuncture Needle Selection on Symptom Relief and Patient Tolerance in the Treatment of Pain
Who cites it
86 citing papers in PubMed, 16 syntheses or guidelines pooled it, 171 citations in OpenAlex.
- Western medical acupuncture techniques for pain management in athletes: a systematic review and meta-analysis.Frontiers in medicine · 2026Pooled it
- Core acupoint selection strategies and multifactorial analysis for acute musculoskeletal pain.Frontiers in medicine · 2026Pooled it
- Bee venom acupuncture for musculoskeletal pain conditions: an updated systematic review and meta-analysis.BMC complementary medicine and therapies · 2025Pooled it
- Factors and Their Impact on Treatment Effect of Acupuncture in Different Outcomes: A Meta-Regression of Acupuncture Randomized Controlled Trials.Chinese journal of integrative medicine · 2024Pooled it
- The Effects of Anthroposophic Medicine in Chronic Pain Conditions: A Systematic Review.Journal of integrative and complementary medicine · 2023Pooled it
- Use of Acupuncture for Adult Health Conditions, 2013 to 2021: A Systematic Review.JAMA network open · 2022Pooled it
- A Systematic Review of Practiced-Based Research of Complementary and Integrative Health Therapies as Provided for Pain Management in Clinical Settings: Recommendations for the Future and a Call to Action.Pain medicine (Malden, Mass.) · 2022Pooled it
- Coordinate-based (ALE) meta-analysis of acupuncture for musculoskeletal pain.Frontiers in neuroscience · 2022Pooled it
- A coordinate-based meta-analysis of acupuncture for chronic pain: Evidence from fMRI studies.Frontiers in neuroscience · 2022Pooled it
- Acupuncture for post-stroke depression: a systematic review and meta-analysis.BMC complementary medicine and therapies · 2021Pooled it
- Use of Acupuncture for the Treatment of Sports-Related Injuries in Athletes: A Systematic Review of Case Reports.International journal of environmental research and public health · 2020Pooled it
- Acupuncture for Rehabilitation After Total Knee Arthroplasty: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Frontiers in medicine · 2020Pooled it
- Acupuncture for the Relief of Chronic Pain: A Synthesis of Systematic Reviews.Medicina (Kaunas, Lithuania) · 2019Pooled it
- Functional Somatic Symptoms.Deutsches Arzteblatt international · 2019Pooled it
- Acupuncture in adults with Chemotherapy-Induced Peripheral Neuropathy: a systematic review.Revista latino-americana de enfermagem · 2019Pooled it
- Non-pharmacological Interventions on Pain and Quality of Life in Chemotherapy Induced Polyneuropathy: Systematic Review and Meta-Analysis.In vivo (Athens, Greece)Pooled it
- Immediate analgesic effect of two modes of transcutaneous electrical nerve stimulation on patients with chronic low back pain: a randomized controlled trial.Einstein (Sao Paulo, Brazil) · 2021Trial
- Acupuncture versus Lornoxicam in the Treatment of Acute Renal Colic: A Randomized Controlled Trial.Journal of pain research · 2021Trial
- Trial
- Individual vs. Group Delivery of Acupuncture Therapy for Chronic Musculoskeletal Pain in Urban Primary Care-a Randomized Trial.Journal of general internal medicine · 2020Trial
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims of this systematic review were to study the analgesic effect of real acupuncture and to explore whether sham acupuncture (SA) type is related to the estimated effect of real acupuncture for musculoskeletal pain. Five databases were searched. The outcome was pain or disability immediately (≤1 week) following an intervention. Standardized mean differences (SMDs) with 95% confidence intervals were calculated. Meta-regression was used to explore possible sources of heterogeneity. Sixty-three studies (6382 individuals) were included. Eight condition types were included. The pooled effect size was moderate for pain relief (59 trials, 4980 individuals, SMD -0.61, 95% CI -0.76 to -0.47; P < 0.001) and large for disability improvement (31 trials, 4876 individuals, -0.77, -1.05 to -0.49; P < 0.001). In a univariate meta-regression model, sham needle location and/or depth could explain most or all heterogeneities for some conditions (e.g., shoulder pain, low back pain, osteoarthritis, myofascial pain, and fibromyalgia); however, the interactions between subgroups via these covariates were not significant (P < 0.05). Our review provided low-quality evidence that real acupuncture has a moderate effect (approximate 12-point reduction on the 100-mm visual analogue scale) on musculoskeletal pain. SA type did not appear to be related to the estimated effect of real acupuncture.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.