Trial reportThorax2016
Long-term psychosocial outcomes of low-dose CT screening: results of the UK Lung Cancer Screening randomised controlled trial.
Trial report in Thorax, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Screening for lung cancer: A systematic review of overdiagnosis and its implications.Molecular oncology · 2026Pooled it
- Participant factors associated with psychosocial impacts of lung cancer screening: A systematic review.Cancer medicine · 2024Pooled it
- Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality.The Cochrane database of systematic reviews · 2022Pooled it
- Pooled it
- Guideline
- Guideline
- Effects of low-dose computed tomography on lung cancer screening: a systematic review, meta-analysis, and trial sequential analysis.BMC pulmonary medicine · 2019Pooled it
- Psychological impact of lung cancer screening using a novel antibody blood test followed by imaging: the ECLS randomized controlled trial.Journal of public health (Oxford, England) · 2023Trial
- Trial
- Trial
- Impact of a Lung Cancer Screening Information Film on Informed Decision-making: A Randomized Trial.Annals of the American Thoracic Society · 2019Trial
- Trial
- [White paper on identification, information, and eligibility assessment of potential participants in lung cancer screening in Germany].Pneumologie (Stuttgart, Germany) · 2026Article
- European Code Against Cancer, 5th edition - organised cancer screening programmes.Molecular oncology · 2026Review
- Research on Cancer Prediction Based on Feature Optimization and Multimodal Fusion.Health care science · 2025Article
- Structured narrative review on lung cancer screening: current evidence, clinical practice implications and implementation insights from a multidisciplinary task force and patient representatives.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Lessons Learned From International Lung Cancer Screening Trials; People at Risk Deserve Screening for Early Detection.Respirology (Carlton, Vic.) · 2025Review
- Patients' experiences of, and psychological responses to, surveillance for pulmonary nodules detected through lung cancer screening.BMJ open respiratory research · 2025Article
- Screening for lung cancer with computed tomography: protocol for systematic reviews for the Canadian Task Force on Preventive Health Care.Systematic reviews · 2024Article
- European lung cancer screening: valuable trial evidence for optimal practice implementation.The British journal of radiology · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundThe UK Lung Cancer Screening (UKLS) trial is a randomised pilot trial of low-dose CT (LDCT) screening for individuals at high risk of lung cancer. We assessed the long-term psychosocial impact on individuals participating in the UKLS trial.
methodsA random sample of individuals aged 50-75 years was contacted via primary care. High-risk individuals who completed T
resultsA total of 4037 high-risk individuals were randomised and they completed T
conclusionLung cancer screening using LDCT appears to have no clinically significant long-term psychosocial impact on high-risk participants. Strategies for engaging and supporting underserved groups are the key to implement routine lung cancer screening in the UK. TRIAL REGISTRATION NUMBER: ISRCTN 78513845; results.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.